Urinary Inorganic Arsenic Concentration and Gestational Diabetes Mellitus in Pregnant Women from Arica, Chile

María Pía Muñoz, Macarena Valdés, María Teresa Muñoz-Quezada, Boris Lucero, Paola Rubilar, Paulina Pino and Verónica Iglesias
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María Pía Muñoz: Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, 8380453 Santiago, Chile
Macarena Valdés: Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, 8380453 Santiago, Chile
María Teresa Muñoz-Quezada: Facultad de Ciencias de la Salud, Universidad Católica del Maule, 3480112 Talca, Chile
Boris Lucero: Facultad de Ciencias de la Salud, Universidad Católica del Maule, 3480112 Talca, Chile
Paola Rubilar: Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, 8380453 Santiago, Chile
Paulina Pino: Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, 8380453 Santiago, Chile
Verónica Iglesias: Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, 8380453 Santiago, Chile

IJERPH, 2018, vol. 15, issue 7, 1-10

Abstract: Introduction: The association of total arsenic exposure with impaired glucose tolerance and gestational diabetes has been shown; however, evidence regarding urinary inorganic arsenic in pregnant women is still limited. Our aim was to evaluate the association between urinary inorganic arsenic concentration and gestational diabetes among pregnant women living in Arica, Chile. Methods: Cross-sectional study of pregnant women receiving care at primary health centers in urban Arica. The exposure was urinary inorganic arsenic concentration, while gestational diabetes was the outcome. The association was evaluated using multiple logistic regression models adjusted by age, education level, ethnicity, and pre-pregnancy body mass index. Results: 244 pregnant women were surveyed. The median urinary inorganic arsenic was 14.95 μg/L, and the prevalence of gestational diabetes was 8.6%. After adjusting, we did not find a significant association between gestational diabetes and inorganic arsenic exposure tertiles (Odds ratio (OR) 2.98, 95% CI = 0.87–10.18), (OR 1.07, 95% CI = 0.26–4.33). Conclusion: This study did not provide evidence on the relationship between urinary inorganic arsenic concentration and gestational diabetes. Further research is needed to elucidate the factors underlying this association.

Keywords: environmental exposure; inorganic arsenic; gestational diabetes; pregnant (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
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