Research Trends and Hotspots Analysis Related to the Effects of Xenobiotics on Glucose Metabolism in Male Testes

Yongsheng Fan, Guangxia Yu, Jun Yu, Jiantao Sun, Yu Wu, Xue Zhao, Yu Meng, Zhangdong He and Chunhong Wang
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Yongsheng Fan: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Guangxia Yu: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Jun Yu: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Jiantao Sun: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Yu Wu: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Xue Zhao: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Yu Meng: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Zhangdong He: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China
Chunhong Wang: Department of Toxicology, School of Public Health, Wuhan University, DongHu Road 115, Wuhan 430071, China

IJERPH, 2018, vol. 15, issue 8, 1-12

Abstract: This study aimed to integrate and analyze the existing studies and to explore research trends and hotspots related to the effects of xenobiotics on glucose metabolism in male testes. All articles were retrieved from the PubMed database, from an inception date up to 10 June 2017. CiteSpace software (version 5.1.R8 SE) was used for the co-word cluster analysis. A total of 165 eligible publications were included in this study. In 1949–1959, only two articles were published. After 1960, the number of articles increased steadily. These articles were published in 97 journals, in particular, in the Indian Journal of Experimental Biology (11 articles, 6.7%). Most of the authors (87.0%) only published one article. Only a few established research teams, mostly from the USA, worked consistently in this field. The main xenobiotics that had been studied were medicine and common environmental pollutants, e.g., gossypol, cadmium, di-n-butyl phthalate, and alpha-chlorohydrin. The hotspot keywords were Sertoli cell, lactate dehydrogenase, 6-phosphate dehydrogenase, oxidative stress, and glucose metabolism. The focus of research had been changed overtime. This is the first bibliometric study between xenobiotics and glucose metabolism in the male testes. The findings suggest that environmental pollutants have become a huge concern, and related research should be strengthened.

Keywords: xenobiotics; glucose metabolism; testes; bibliometrics; CiteSpace (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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