Serum Lipid Profile and Its Association with Diabetes and Prediabetes in a Rural Bangladeshi Population

Bishwajit Bhowmik, Tasnima Siddiquee, Anindita Mujumder, Faria Afsana, Tareen Ahmed, Ibrahimu A. Mdala, Nayla Cristina Do V. Moreira, Abul Kalam Azad Khan, Akhtar Hussain, Gerd Holmboe-Ottesen and Tone Kristin Omsland
Additional contact information
Bishwajit Bhowmik: Department of Community Medicine and Global Health, University of Oslo, 0318 Oslo, Norway
Tasnima Siddiquee: Centre for Global Health Research, Diabetic Association of Bangladesh, Dhaka 1000, Bangladesh
Anindita Mujumder: Department of Pathology, Ibrahim Medical College, Diabetic Association of Bangladesh, Dhaka 1000, Bangladesh
Faria Afsana: Bangladesh Institute of Research & Rehabilitation of Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka 1000, Bangladesh
Tareen Ahmed: Bangladesh Institute of Research & Rehabilitation of Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka 1000, Bangladesh
Ibrahimu A. Mdala: Department of Community Medicine and Global Health, University of Oslo, 0318 Oslo, Norway
Nayla Cristina Do V. Moreira: Department of Community Medicine and Global Health, University of Oslo, 0318 Oslo, Norway
Abul Kalam Azad Khan: Centre for Global Health Research, Diabetic Association of Bangladesh, Dhaka 1000, Bangladesh
Akhtar Hussain: Centre for Global Health Research, Diabetic Association of Bangladesh, Dhaka 1000, Bangladesh
Gerd Holmboe-Ottesen: Department of Community Medicine and Global Health, University of Oslo, 0318 Oslo, Norway
Tone Kristin Omsland: Department of Community Medicine and Global Health, University of Oslo, 0318 Oslo, Norway

IJERPH, 2018, vol. 15, issue 9, 1-12

Abstract: Dyslipidemia is commonly associated with diabetes (T2DM). This has been demonstrated for the Caucasian population, but few data are available for Asian Indians. The paper aims to investigate serum lipids (separately or in combination) and their association with glucose intolerance status (T2DM and prediabetes) in a rural Bangladeshi population. A sample of 2293 adults (≥20 years) were included in a community based cross-sectional survey in 2009. Anthropometric measures, blood pressure, blood glucose (fasting and 2-h oral glucose tolerance test) and fasting serum lipids (total cholesterol, T-Chol; triglycerides, Tg; low density lipoprotein cholesterol, LDL-C and high density lipoprotein cholesterol, HDL-C) were registered. Analysis of covariance (ANCOVA) and regression analysis were performed. High Tg levels were seen in 26% to 64% of the participants, depending on glucose tolerance status. Low HDL-C levels were seen in all groups (>90%). Significant linear trends were observed for high T-Chol, high Tg and low HDL-C with increasing glucose intolerance ( p for trend <0.001). T2DM was significantly associated with high T-Chol (Odds ratio (OR): 2.43, p < 0.001), high Tg (OR: 3.91, p < 0.001) and low HDL-C (OR: 2.17, p = 0.044). Prediabetes showed a significant association with high Tg (OR: 1.96, p < 0.001) and low HDL-C (OR: 2.93, p = 0.011). Participants with combined high Tg and low HDL-C levels had a 12.75-fold higher OR for T2DM and 4.89 OR for prediabetes. In Asian Indian populations an assessment of serum lipids is warranted not only for T2DM patients, but also for those with prediabetes.

Keywords: lipid profile; diabetes; prediabetes; Bangladesh (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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