Association of Environmental Features and the Risk of Alzheimer’s Dementia in Older Adults: A Nationwide Longitudinal Case-Control Study

Chih-Ching Liu, Chung-Yi Li, Shiann-Far Kung, Hsien-Wen Kuo, Nuan-Ching Huang, Yu Sun and Susan C. Hu
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Chih-Ching Liu: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
Chung-Yi Li: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
Shiann-Far Kung: Department of Urban Planning, National Cheng Kung University, Tainan 701, Taiwan
Hsien-Wen Kuo: Institute of Environmental and Occupational Health Sciences, National Yang-Ming University, Taipei 112, Taiwan
Nuan-Ching Huang: Healthy Cities Research Center, Research and Services Headquarters, National Cheng Kung University, Tainan 701, Taiwan
Yu Sun: Department of Neurology, En Chu Kong Hospital, New Taipei City 23702, Taiwan
Susan C. Hu: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan

IJERPH, 2019, vol. 16, issue 16, 1-16

Abstract: Little is known about the association between environmental features and the risk of Alzheimer’s dementia (AD). This study aims to investigate the association of physical and social environments with the incidence of AD. We identified 12,401 newly diagnosed AD cases aged ≥65 years in 2010, with the same no. of matched controls from National Health Insurance claims in Taiwan. Environmental data were collected from government statistics including three physical environments and three social environments. Multilevel logistic regression was conducted to calculate the odds ratios (OR) of AD in association with environmental features at the township level. Results showed that living in the areas with higher availability of playgrounds and sport venues was associated with a 3% decreased odds of AD (95% CI = 0.96–0.99), while higher density of elderly living alone was associated with a 5% increased odds of AD (95% CI = 1.01–1.11), after controlling for individual and other environmental factors. In further examination by urbanization level, the above relationships were found only in rural areas but not in urban areas. This study provides evidence that specific physical and social environmental features have different impacts on the risk of AD.

Keywords: physical environments; social environments; Alzheimer’s dementia; incidence; case-control study; longitudinal study (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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