Diet and Non-Alcoholic Fatty Liver Disease: The Mediterranean Way

Ludovico Abenavoli, Luigi Boccuto, Alessandro Federico, Marcello Dallio, Carmelina Loguercio, Laura Di Renzo and Antonino De Lorenzo
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Ludovico Abenavoli: Department of Health Sciences, University “Magna Graecia”, Viale Europa—Germaneto, 88110 Catanzaro, Italy
Luigi Boccuto: Greenwood Genetic Center, 113 Gregor Mendel Circle, Greenwood, SC 29646, USA
Alessandro Federico: Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, via Pansini 5, 80131 Naples, Italy
Marcello Dallio: Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, via Pansini 5, 80131 Naples, Italy
Carmelina Loguercio: Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, via Pansini 5, 80131 Naples, Italy
Laura Di Renzo: Department of Biomedicine and Prevention, Section of Clinical Nutrition and Nutrigenomic, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
Antonino De Lorenzo: Department of Biomedicine and Prevention, Section of Clinical Nutrition and Nutrigenomic, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy

IJERPH, 2019, vol. 16, issue 17, 1-9

Abstract: Lifestyle interventions remain the first-line treatment for non-alcoholic fatty liver disease (NAFLD), even if the optimal alimentary regimen is still controversial. The interest in antioxidants has increased over time, and literature reports an inverse association between nutrients rich in antioxidants and the risk of mortality due to non-communicable diseases, including NAFLD. Mediterranean diet (MD) is a model characterized by main consumption of plant-based foods and fish and reduced consumption of meat and dairy products. MD represents the gold standard in preventive medicine, probably due to the harmonic combination of many foods with antioxidant and anti-inflammatory properties. This regimen contributes substantially to the reduction of the onset of many chronic diseases as cardiovascular diseases, hypertension, type 2 diabetes mellitus, obesity, cancer, and NAFLD. The present review aims to clarify the intake of antioxidants typical of the MD and evaluate their effect on NAFLD.

Keywords: metabolism; steatosis; inflammation; polyphenols; microbiota (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
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