Skin Melanoma and Subsequent Risk of Prostate Cancer: A Lithuanian Cancer Registry Study

Ausvydas Patasius, Vincas Urbonas and Giedre Smailyte
Additional contact information
Ausvydas Patasius: Laboratory of Cancer Epidemiology, National Cancer Institute, Santariskiu 1, LT-08660 Vilnius, Lithuania
Vincas Urbonas: Laboratory of Clinical Oncology, National Cancer Institute, Santariskiu 1, LT-08660 Vilnius, Lithuania
Giedre Smailyte: Laboratory of Cancer Epidemiology, National Cancer Institute, Santariskiu 1, LT-08660 Vilnius, Lithuania

IJERPH, 2019, vol. 16, issue 20, 1-5

Abstract: Emerging data indicates that melanoma may be linked to prostate cancer. We evaluated if the incidence of melanoma was associated with subsequent risk of prostate cancer (PC). We extracted data from the Lithuanian cancer registry from 1993 to 2012. We calculated the standardized incidence ratios (SIRs) for PC as a ratio of observed number of cancer cases in people with previous melanoma diagnosis to the expected number of cancer cases in the underlying general population. Therein, 95% confidence intervals for the SIRs were estimated assuming the number of observed cancer cases follows the Poisson distribution. Overall, 65 PCs were observed versus 52.5 expected (SIR 1.24; 95% CI: 0.97–1.58) within a period of 24 years. A significantly increased risk of PC was found in patients with melanoma diagnosis over 70 years (SIR 1.62; 95% CI: 1.11–2.39) and in two periods of diagnosis (SIRs 1.76 and 1.62 in 1993–1997 and 2009–2012, respectively). A significantly increased risk was also found five to nine years after melanoma diagnosis (SIR 1.58; 95% CI: 1.05–2.38). Further studies are needed to evaluate the relationship between melanoma and subsequent risk of prostate cancer.

Keywords: melanoma; prostate cancer; cancer registry; epidemiology (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/16/20/3915/pdf (application/pdf)
https://www.mdpi.com/1660-4601/16/20/3915/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:16:y:2019:i:20:p:3915-:d:276679

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().