Work-Related Stress, Physio-Pathological Mechanisms, and the Influence of Environmental Genetic Factors

Emanuele Cannizzaro, Tiziana Ramaci, Luigi Cirrincione and Fulvio Plescia
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Emanuele Cannizzaro: Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities “Giuseppe D’Alessandro”, University of Palermo, via del Vespro 133, 90127 Palermo, Italy
Tiziana Ramaci: Faculty of Human and Social Sciences, Kore University of Enna, 94100 Enna, Italy
Luigi Cirrincione: Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities “Giuseppe D’Alessandro”, University of Palermo, via del Vespro 133, 90127 Palermo, Italy
Fulvio Plescia: Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities “Giuseppe D’Alessandro”, University of Palermo, via del Vespro 133, 90127 Palermo, Italy

IJERPH, 2019, vol. 16, issue 20, 1-10

Abstract: Work-related stress is a growing health problem in modern society. The stress response is characterized by numerous neurochemicals, neuroendocrine and immune modifications that involve various neurological systems and circuits, and regulation of the gene expression of the different receptors. In this regard, a lot of research has focused the attention on the role played by the environment in influencing gene expression, which in turn can control the stress response. In particular, genetic factors can moderate the sensitivities of specific types of neural cells or circuits mediating the imprinting of the environment on different biological systems. In this current review, we wish to analyze systematic reviews and recent experimental research on the physio-pathological mechanisms that underline stress-related responses. In particular, we analyze the relationship between genetic and epigenetic factors in the stress response.

Keywords: work-related stress; environment; genetic factors; stress (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (5)

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