Determination of Triglycidyl Isocyanurate in Workplace Air

Anna Jeżewska and Joanna Kowalska
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Anna Jeżewska: Central Institute for Labour Protection – National Research Institute, Czerniakowska 16, 00-701 Warsaw, Poland
Joanna Kowalska: Central Institute for Labour Protection – National Research Institute, Czerniakowska 16, 00-701 Warsaw, Poland

IJERPH, 2019, vol. 16, issue 22, 1-10

Abstract: Triglycidyl isocyanurate (TGIC) is a white solid in powder or granular form. TGIC does not occur naturally in the environment. It is intentionally manufactured and used as a crosslinking agent or hardener to produce polyester powder coatings. TGIC may cause genetic defects. This article presents the method of TGIC determination in workplace air using high-performance liquid chromatography (HPLC) with a diode-array detector (DAD). The method is based on the collection of TGIC present in the air on a polypropylene filter, extraction with acetonitrile, and chromatographic analysis of the solution obtained in this way. The determination was carried out in the reverse-phase system (mobile phase: acetonitrile: water) using an Ultra C18 column. The measurement range is 2 to 40 µg/m 3 for a 720 liters air sample. Limit of detection (LOD) is 23 ng/m 3 and limit of quantification (LOQ): 70 ng/m 3 . The method can be used for assessing occupational exposure to TGIC and associated risk to workers’ health.

Keywords: TGIC; tris (2,3-epoxypropyl) isocyanurate; mutagenic substance; air pollution; occupational exposure; chromatography; health sciences; environmental engineering (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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