Thermoregulation in Ectodermal Dysplasia: A Case Series

Heather Massey, James House and Michael Tipton
Additional contact information
Heather Massey: Extreme Environments Laboratory, School of Sport, Health and Exercise Science, University of Portsmouth, Portsmouth PO1 2ER, UK
James House: Extreme Environments Laboratory, School of Sport, Health and Exercise Science, University of Portsmouth, Portsmouth PO1 2ER, UK
Michael Tipton: Extreme Environments Laboratory, School of Sport, Health and Exercise Science, University of Portsmouth, Portsmouth PO1 2ER, UK

IJERPH, 2019, vol. 16, issue 22, 1-9

Abstract: Ectodermal dysplasia (ED) is a rare genetic disorder occurring as a consequence of gene mutations that code for the ectoderm of the developing embryo and results in numerous disorders of varying severity. The lack of functioning sweat glands in those affected with ED leads to high infant mortality and frequent complaints of hyperthermia. Temperature control of two adolescents affected with ED was assessed by conducting heat and exercise exposures while monitoring insulated auditory canal (T ac ) and skin temperatures, sweating rates, and skin blood flow. One participant was able to sweat and regulate his T ac while a second participant could not regulate T ac without a cooling intervention. The heterogeneous nature of ED, and these cases highlight the need for a case-by-case review of temperature control of individuals affected with ED. This will determine cooling strategies that would be of most benefit to the individual.

Keywords: hyperthermia; hereditary disorders; hypohidrosis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/16/22/4514/pdf (application/pdf)
https://www.mdpi.com/1660-4601/16/22/4514/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:16:y:2019:i:22:p:4514-:d:287238

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().