Cytotoxicity Assessment of PM 2.5 Collected from Specific Anthropogenic Activities in Taiwan

Tuan Hung Ngo, Pei Chun Tsai, Yune-Fang Ueng and Kai Hsien Chi
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Tuan Hung Ngo: Institute of Environmental and Occupational Health Sciences, National Yang Ming University, Taipei 112, Taiwan
Pei Chun Tsai: Institute of Environmental and Occupational Health Sciences, National Yang Ming University, Taipei 112, Taiwan
Yune-Fang Ueng: Divisions of Basic Chinese Medicine, National Research Institute of Chinese Medicine, Taipei 112, Taiwan
Kai Hsien Chi: Institute of Environmental and Occupational Health Sciences, National Yang Ming University, Taipei 112, Taiwan

IJERPH, 2019, vol. 16, issue 24, 1-12

Abstract: Fine particulate matter (PM 2.5 ) from different sources with different components have different health impact. In this research in Taiwan, composition and cytotoxicity of PM 2.5 from long-range transport event (LRT), traffic activity, and outdoor cooking at night market were studied. The PM 2.5 mass concentrations were 39.0 μg/m 3 during LRT, 42.9 μg/m 3 at traffic area, and 28.3 μg/m 3 at the night market. Traffic area had highest concentrations of PCDD/Fs (46.9 fg I-TEQ/m 3 ) when highest PAH concentrations of 3.57 BaPeq-ng/m 3 were found at night market area. One quarter of PM 2.5 mass at LRT and night market was constituted by water-soluble ion (26.02–28.93%). Road dust (represented by high concentration of Al and Ca) was the main contributor for metal element at traffic station whereas presence of natural salt (Na and Cl elements) was a marker of LRT and cooking activities. Cell viability reduced 9% after exposure to organic extracts of 0.316 μg of PM 2.5 from LRT and night market samples. 150% elevation of ROS production was observed after exposure with organic compound of night market samples at the dose equivalent to 10.0 μg PM 2.5 . Organic extracts from night market induced positive genotoxicity in umu test (at a dose of 20.0 μg PM 2.5 ).

Keywords: PM 2.5; cell toxicity; long-range transport; traffic activity; cooking activity (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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