A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients

Chang-Yu Lee, Cheuk-Sing Choy, Yu-Cheng Lai, Chao-Chien Chang, Nai-Chia Teng, Wan-Ting Huang, Che-Tong Lin and Yung-Kai Huang
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Chang-Yu Lee: Division of Periodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan
Cheuk-Sing Choy: Department of Community Medicine, En Chu Kong Hospital, New Taipei City 237, Taiwan
Yu-Cheng Lai: Department of Dentistry, En Chu Kong Hospital, New Taipei City 237, Taiwan
Chao-Chien Chang: Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
Nai-Chia Teng: School of Dentistry, College of Oral Medicine, Taipei Medical University; Taipei 110, Taiwan
Wan-Ting Huang: School of Dentistry, College of Oral Medicine, Taipei Medical University; Taipei 110, Taiwan
Che-Tong Lin: School of Dentistry, College of Oral Medicine, Taipei Medical University; Taipei 110, Taiwan
Yung-Kai Huang: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan

IJERPH, 2019, vol. 16, issue 2, 1-16

Abstract: Periodontitis is an inflammatory disease, wherein endogenous antioxidants help to balance the inflammatory status. Oral health behaviors are related to the periodontal disease status. The aim of this study was to explore the associations between oral health behaviors and endogenous antioxidants in periodontitis patients. In total, 225 subjects diagnosed with periodontitis were enrolled in the study. Information obtained from the initial interview included socioeconomic and demographic characteristics, lifestyle factors, and oral health-related behaviors. The clinical periodontal parameters evaluated included bleeding on probing (BOP), the plaque index (PI), and probing depth (PD). Stimulated saliva was collected before periodontal therapy to determine five endogenous antioxidants (copper-zinc superoxide dismutase (Cu/Zn SOD), manganese SOD (MnSOD), thioredoxin 1 (Trx1), peroxiredoxin 2 (Prx2), and catalase (CAT)). When these five factors were adjusted for in patients whose last previous dental visit was >1 year, the patients’ PI, BOP, and PD showed significant decreases because of an elevation in the Cu/Zn SOD level. Associations of endogenous antioxidants with levels of clinical periodontal parameters were much higher in subjects whose last previous dental visit was >1 year, compared to subjects whose last previous dental visit was <1 year. This study provides a better understanding of dental visit patterns and the salivary endogenous antioxidants that may underlie the symptomatic development of preclinical periodontitis.

Keywords: salivary biomarker; dental visit; oxidative stress response; periodontitis; prevention (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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