Effect of an 8-Week Individualized Training Program on Blood Biomarkers, Adipokines and Endothelial Function in Obese Young Adolescents with and without Metabolic Syndrome

Mohamed Sami Zguira, Maamer Slimani, Nicola Luigi Bragazzi, Meriem Khrouf, Faten Chaieb, Bernard Saïag and Zouhair Tabka
Additional contact information
Mohamed Sami Zguira: Higher Institute of Sport and Physical Education of Gafsa, Gafsa 2100, Tunisia
Maamer Slimani: Postgraduate School of Public Health, Department of Health Sciences (DISSAL), Genoa University, 16132 Genoa, Italy
Nicola Luigi Bragazzi: Postgraduate School of Public Health, Department of Health Sciences (DISSAL), Genoa University, 16132 Genoa, Italy
Meriem Khrouf: Hôpital Universitaire Fattouma Bourguiba, Cardiologie, Monastir 5000, Tunisia
Faten Chaieb: Department of Physiology and Lung Function Testing, Faculty of Medicine Ibn-El-Jazzar, University of Sousse, Sousse 4000, Tunisia
Bernard Saïag: Laboratory “Movement Sport and Health Sciences”, UFR APS University of Rennes 2, Avenue Charles Tillon, 35044 Rennes CEDEX, France
Zouhair Tabka: Department of Physiology and Lung Function Testing, Faculty of Medicine Ibn-El-Jazzar, University of Sousse, Sousse 4000, Tunisia

IJERPH, 2019, vol. 16, issue 5, 1-12

Abstract: Obesity is a chronic condition whose incidence is growing due to lack of exercise and frequent nutrition disorders. Childhood obesity has reached epidemic proportions worldwide. One of the best treatment methods is physical training. However, conflicting results have been reported regarding its clinical effectiveness. These contrasting findings may be due to the type and intensity of the adopted physical training program. Therefore, the purpose of the current study was to investigate the effect of an 8-week individualized physical training program on endothelial function, blood biomarkers and adipokine levels in obese adolescents with and without metabolic syndrome (MS). One-hundred-and-twenty-two obese adolescents (71 obese without MS and 51 obese with MS) aged 14 ± 2 years were included in this study. The 8-week individualized training program decreased glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol and leptin in obese subjects with and without MS. However, adiponectin and endothelial-dependent vasodilatation increased in the follow-up study in both groups. Taken together, the findings suggest that individualized training program is an effective means for the treatment of obesity and MS in pediatric populations.

Keywords: individualized training program; diabetes and metabolic syndrome; obesity; blood biomarkers; adipokines; endothelial function (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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