Relationship between Secondhand Smoke Exposure and Depressive Symptoms: A Systematic Review and Dose–Response Meta-Analysis

Changlin Han, Yangqun Liu, Xiao Gong, Xiaohua Ye and Junli Zhou
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Changlin Han: School of Public Health, Guangdong Pharmaceutical University, 283 Jianghai Dadao, Haizhu District, Guangzhou 510310, China
Yangqun Liu: School of Public Health, Guangdong Pharmaceutical University, 283 Jianghai Dadao, Haizhu District, Guangzhou 510310, China
Xiao Gong: School of Public Health, Guangdong Pharmaceutical University, 283 Jianghai Dadao, Haizhu District, Guangzhou 510310, China
Xiaohua Ye: School of Public Health, Guangdong Pharmaceutical University, 283 Jianghai Dadao, Haizhu District, Guangzhou 510310, China
Junli Zhou: School of Public Health, Guangdong Pharmaceutical University, 283 Jianghai Dadao, Haizhu District, Guangzhou 510310, China

IJERPH, 2019, vol. 16, issue 8, 1-14

Abstract: Previous studies have suggested an association between secondhand smoke (SHS) exposure and risk of depressive symptoms. However, it remains unclear whether there is a dose–response relationship. The effect estimates were pooled using fixed-effect or random-effect models based on homogeneity analysis. The dose–response meta-analysis was performed by linear and non-linear regression. Subgroup analyses were conducted to explore the possible sources of heterogeneity. Twenty-four studies were included in this meta-analysis. SHS exposure was significantly associated with increased odds of depressive symptoms (odds ratio (OR) = 1.32, 95% confidence interval (CI) 1.25–1.39). For SHS exposure expressed as an ordinal variable, the dose–response meta-analysis revealed a monotonically increasing relationship between SHS exposure and depressive symptoms. A similar dose–response relationship was observed for SHS exposure expressed as a continuous variable (OR = 1.57, 95% CI = 1.26–1.87). Our findings suggest that SHS exposure is associated with increasing odds of depressive symptoms in a dose–response manner.

Keywords: secondhand smoke; depressive symptoms; depression; epidemiology discipline (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
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Citations: View citations in EconPapers (2)

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