Maternal Occupational Oil Mist Exposure and Birth Defects, National Birth Defects Prevention Study, 1997–2011

Miriam Siegel, Carissa M. Rocheleau, Candice Y. Johnson, Martha A. Waters, Christina C. Lawson, Tiffany Riehle-Colarusso, Jennita Reefhuis and The National Birth Defects Prevention Study
Additional contact information
Miriam Siegel: Epidemic Intelligence Service, Center for Surveillance, Epidemiology and Laboratory Services, Atlanta, GA 30329, USA
Carissa M. Rocheleau: Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
Candice Y. Johnson: Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
Martha A. Waters: Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Cincinnati, OH 45226
Christina C. Lawson: Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
Tiffany Riehle-Colarusso: Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30329, USA
Jennita Reefhuis: Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30329, USA
The National Birth Defects Prevention Study: Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30329, USA

IJERPH, 2019, vol. 16, issue 9, 1-12

Abstract: Workers in various industries can be exposed to oil mists when oil-based fluids are aerosolized during work processes. Oil mists can be inhaled or deposited on the skin. Little research exists on the reproductive effects of oil mist exposure in pregnant workers. We aimed to investigate associations between occupational oil mist exposure in early pregnancy and a spectrum of birth defects using data from 22,011 case mothers and 8140 control mothers in the National Birth Defects Prevention Study. In total, 150 mothers were rated as exposed. Manufacturing jobs, particularly apparel manufacturing, comprised the largest groups of exposed mothers. Mothers of infants with septal heart defects (odds ratio (OR): 1.8, 95% confidence interval (CI): 1.0–3.3), and especially perimembranous ventricular septal defects (OR: 2.5, CI: 1.2–5.2), were more likely to be occupationally exposed to oil mists in early pregnancy than control mothers; and their rater-estimated cumulative exposure was more likely to be higher. This was the first U.S. study evaluating associations between oil mist exposure and a broad spectrum of birth defects. Our results are consistent with previous European studies, supporting a potential association between oil-based exposures and congenital heart defects. Further research is needed to evaluate the reproductive effects of occupational oil mist exposure.

Keywords: birth defects; congenital heart defects; oil mists; occupational exposure (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/16/9/1560/pdf (application/pdf)
https://www.mdpi.com/1660-4601/16/9/1560/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:16:y:2019:i:9:p:1560-:d:228161

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().