Effects of Resistance Exercise on Glycated Hemoglobin and Functional Performance in Older Patients with Comorbid Diabetes Mellitus and Knee Osteoarthritis: A Randomized Trial

Shu-Mei Chen, Feng-Chih Shen, Jung-Fu Chen, Wen-Dien Chang and Nai-Jen Chang
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Shu-Mei Chen: Department of Sports Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Feng-Chih Shen: Division of Endocrinology & Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Jung-Fu Chen: Division of Endocrinology & Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Wen-Dien Chang: Department of Sport Performance, National Taiwan University of Sport, Taichung 404, Taiwan
Nai-Jen Chang: Department of Sports Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan

IJERPH, 2019, vol. 17, issue 1, 1-13

Abstract: Type 2 diabetes mellitus (T2DM) is significantly associated with osteoarthritis (OA). This study investigated the effects of two resistance exercise approaches on glycated hemoglobin (HbA1c) level and function performance. Enrolled were 70 older patients with both T2DM and knee OA. The dynamic group performed resistance exercises with an elastic resistance band. The isometric group underwent isometric contraction exercises. After the 12-week intervention, a significant within-group improvement (all p < 0.001) was observed for the chair stand test (CST; 10.8%, vs. 7.1%), timed up and go (TUG) test (12.6% vs. 7.6%), Western Ontario and McMaster Universities Osteoarthritis (WOMAC) physical function subscale (62.3% vs. 36.1%), and overall WOMAC (54.5% vs. 34.5%) in the dynamic and isometric group, respectively. In addition, in terms of between-group differences, the dynamic group had significant improvements in CST ( p = 0.011), TUG ( p < 0.001), WOMAC physical function subscale ( p = 0.033), and overall WOMAC ( p = 0.036) scores compared with the isometric group. However, no significant change in HbA1c was observed in either group. In conclusion, the dynamic resistance exercise significantly improved muscle strength, dynamic balance, and physical function in this comorbid population; however, there was no notable difference in change in HbA1c among different resistance exercises.

Keywords: therapeutic exercise; physical activity; diabetes; performance; osteoarthritis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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