Interleukin-6 and Melatonin as Predictors of Cognitive, Emotional and Functional Ageing of Older People

Anna Kurowska, Iwona Bodys-Cupak, Magdalena Staszkiewicz, Joanna Szklarczyk, Joanna Zalewska-Puchała, Anna Kliś-Kalinowska, Marta Makara-Studzińska and Anna Majda
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Anna Kurowska: Laboratory of Theory and Fundamentals of Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland
Iwona Bodys-Cupak: Laboratory of Theory and Fundamentals of Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland
Magdalena Staszkiewicz: Department of Clinical Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Kopernika 25, 31-501 Krakow, Poland
Joanna Szklarczyk: Department of Medical Physiology, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland
Joanna Zalewska-Puchała: Laboratory of Theory and Fundamentals of Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland
Anna Kliś-Kalinowska: Laboratory of Theory and Fundamentals of Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland
Marta Makara-Studzińska: Department of Health Psychology, Institute of Nursing and Midwifery, Faculty of Health Sciences Jagiellonian University Medical College, ul. Kopernika 25, 31-501 Krakow, Poland
Anna Majda: Laboratory of Theory and Fundamentals of Nursing, Institute of Nursing and Midwifery, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Michałowskiego 12, 31-126 Krakow, Poland

IJERPH, 2020, vol. 17, issue 10, 1-15

Abstract: Background: The ageing process causes a number of changes in the human immune and endocrine systems. The aim of this study was to assess the relationship between cognitive, emotional and functional skills as well lifestyle, versus selected biochemical indicators of the ageing process. Methods: The cross-sectional study was conducted in a group of 121 people aged 60–90 residing in the Lesser Poland voivodship. The study used standardized research tools including the Barthel scale, Instrumental Activities of Daily Living (IADL) scale, Mini-Mental State Examination (MMSE), Life Orientation Test (LOT-R) and inventory of health behaviors (IHB). In addition, the concentration of IL-6 and melatonin in the blood plasma was determined. Results: We determined the correlation between the level of IL-6 in a group of people over 75 years of age (requiring medical care), and results of the IADL scale. There was also a correlation between melatonin levels and the MMSE results in a group of people aged 60–75 who did not require constant medical care. Conclusions: IL-6 can be treated as a predictor of functional skills of people over 75 years of age, and melatonin can be perceived as a factor for recognizing cognitive impairment in elderly people who do not require constant medical assistance.

Keywords: melatonin; interleukin; ageing; functional skills; cognitive skills; emotional skills (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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