Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis

Vincenza Gianfredi, Lorenzo Blandi, Stefano Cacitti, Mirko Minelli, Carlo Signorelli, Andrea Amerio and Anna Odone
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Vincenza Gianfredi: School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy
Lorenzo Blandi: Accademia Lombarda di Sanità Pubblica, Consorzio Pavese Studi Post-Universitari, Unit of Forensic Medicine and Forensic Sciences, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy
Stefano Cacitti: Accademia Lombarda di Sanità Pubblica, Consorzio Pavese Studi Post-Universitari, Unit of Forensic Medicine and Forensic Sciences, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy
Mirko Minelli: Accademia Lombarda di Sanità Pubblica, Consorzio Pavese Studi Post-Universitari, Unit of Forensic Medicine and Forensic Sciences, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy
Carlo Signorelli: School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy
Andrea Amerio: Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Section of Psychiatry, University of Genoa, 16132 Genoa, Italy
Anna Odone: School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy

IJERPH, 2020, vol. 17, issue 10, 1-20

Abstract: Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was −1.16 [(95% CI = −1.41; −0.91), p -value < 0.001] based on 37,408 participants. The results of the meta-analysis showed a potential protective effect of PA on prevalent and incident depression.

Keywords: depressive symptoms; depression; physical activity; accelerometer; objectively measure; meta-analysis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (9)

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