Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies

Sokhna Dieng, Pierre Michel (), Abdoulaye Guindo, Kankoe Sallah, El-Hadj Ba, Badara Cissé, Maria Patrizia Carrieri, Cheikh Sokhna, Paul Milligan and Jean Gaudart
Additional contact information
Sokhna Dieng: Sciences Economiques et Sociales de la Santé et Traitement de de l’Information Médicale (SESSTIM), Institut de Recherche pour le Développement (IRD), Institut National de la Santé et de la Recherche médicale (INSERM), Aix Marseille Université, 13005 Marseille, France
Abdoulaye Guindo: Sciences Economiques et Sociales de la Santé et Traitement de de l’Information Médicale (SESSTIM), Institut de Recherche pour le Développement (IRD), Institut National de la Santé et de la Recherche médicale (INSERM), Aix Marseille Université, 13005 Marseille, France
Kankoe Sallah: Sciences Economiques et Sociales de la Santé et Traitement de de l’Information Médicale (SESSTIM), Institut de Recherche pour le Développement (IRD), Institut National de la Santé et de la Recherche médicale (INSERM), Aix Marseille Université, 13005 Marseille, France
El-Hadj Ba: Unité Mixte de Recherche (UMR), Vecteurs-Infections Tropicales et Méditerranéennes (VITROME), Campus International Institut de Recherche pour le Développement-Université Cheikh Anta Diop (IRD-UCAD) de l’IRD, Dakar CP 18524, Senegal
Badara Cissé: Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formation (IRESSEF) Diamniadio, Dakar BP 7325, Senegal
Maria Patrizia Carrieri: Sciences Economiques et Sociales de la Santé et Traitement de de l’Information Médicale (SESSTIM), Institut de Recherche pour le Développement (IRD), Institut National de la Santé et de la Recherche médicale (INSERM), Aix Marseille Université, 13005 Marseille, France
Cheikh Sokhna: Unité Mixte de Recherche (UMR), Vecteurs-Infections Tropicales et Méditerranéennes (VITROME), Campus International Institut de Recherche pour le Développement-Université Cheikh Anta Diop (IRD-UCAD) de l’IRD, Dakar CP 18524, Senegal
Paul Milligan: London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Jean Gaudart: Aix Marseille Université, Assistance Publique—Hôpitaux de Marseille(APHM), INSERM, IRD, SESSTIM, Hop Timone, BioSTIC, Biostatistic and ICT, 13005 Marseille, France

IJERPH, 2020, vol. 17, issue 11, 1-23

Abstract: We introduce an approach based on functional data analysis to identify patterns of malaria incidence to guide effective targeting of malaria control in a seasonal transmission area. Using functional data method, a smooth function (functional data or curve) was fitted from the time series of observed malaria incidence for each of 575 villages in west-central Senegal from 2008 to 2012. These 575 smooth functions were classified using hierarchical clustering (Ward’s method), and several different dissimilarity measures. Validity indices were used to determine the number of distinct temporal patterns of malaria incidence. Epidemiological indicators characterizing the resulting malaria incidence patterns were determined from the velocity and acceleration of their incidences over time. We identified three distinct patterns of malaria incidence: high-, intermediate-, and low-incidence patterns in respectively 2% (12/575), 17% (97/575), and 81% (466/575) of villages. Epidemiological indicators characterizing the fluctuations in malaria incidence showed that seasonal outbreaks started later, and ended earlier, in the low-incidence pattern. Functional data analysis can be used to identify patterns of malaria incidence, by considering their temporal dynamics. Epidemiological indicators derived from their velocities and accelerations, may guide to target control measures according to patterns.

Keywords: functional data analysis; time series clustering; malaria patterns; malaria dynamic (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.mdpi.com/1660-4601/17/11/4168/pdf (application/pdf)
https://www.mdpi.com/1660-4601/17/11/4168/ (text/html)

Related works:
Working Paper: Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies (2020)
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:17:y:2020:i:11:p:4168-:d:370217

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().