Effects of the 5-m Shuttle Run Test on Markers of Muscle Damage, Inflammation, and Fatigue in Healthy Male Athletes

Omar Boukhris, Khaled Trabelsi, Raouf Abdessalem, Hsen Hsouna, Achraf Ammar, Jordan M. Glenn, Nick Bott, Khadijah Irandoust, Morteza Taheri, Mouna Turki, Fatma Ayadi, Nicola L. Bragazzi, Florian A. Engel and Hamdi Chtourou
Additional contact information
Omar Boukhris: Activité Physique, Sport et Santé, UR18JS01, Observatoire National du Sport, Tunis 1003, Tunisia
Khaled Trabelsi: Institut Supérieur du Sport et de l’Education Physique de Sfax, Université de Sfax, Sfax 3000, Tunisia
Raouf Abdessalem: Activité Physique, Sport et Santé, UR18JS01, Observatoire National du Sport, Tunis 1003, Tunisia
Hsen Hsouna: Activité Physique, Sport et Santé, UR18JS01, Observatoire National du Sport, Tunis 1003, Tunisia
Achraf Ammar: Institute of Sport Science, Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany
Jordan M. Glenn: Exercise Science Research Center, Department of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR 72701, USA
Nick Bott: Neurotrack Technologies, 399 Bradford St, Redwood City, CA 94063, USA
Khadijah Irandoust: Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin 34148-96818, Iran
Morteza Taheri: Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin 34148-96818, Iran
Mouna Turki: Laboratoire de Biochimie, Centre Hospitalo-universitaire Habib Bourguiba, avenue El-Ferdaous, Sfax 3029, Tunisia
Fatma Ayadi: Laboratoire de Biochimie, Centre Hospitalo-universitaire Habib Bourguiba, avenue El-Ferdaous, Sfax 3029, Tunisia
Nicola L. Bragazzi: Department of Health Sciences (DISSAL), Postgraduate School of Public Health, University of Genoa, 16132 Genoa, Italy
Florian A. Engel: Institute of Sport and Sport Science, Department of Movement and Training Science, Heidelberg University, 69120 Heidelberg, Germany
Hamdi Chtourou: Activité Physique, Sport et Santé, UR18JS01, Observatoire National du Sport, Tunis 1003, Tunisia

IJERPH, 2020, vol. 17, issue 12, 1-16

Abstract: Physical exercise is often associated with increases in muscle damage markers and inflammation. However, biomarkers of muscle damage and inflammation responses to the 5-m shuttle run test (5mSRT) have not yet been evaluated. The aim of the present study was to investigate effects of the 5mSRT on muscle damage markers, inflammation, and perception of fatigue and recovery in healthy male athletes. Fifteen male amateur team sports players (age: 20 ± 3 yrs, height: 173 ± 7 cm, body-mass: 67 ± 7 kg) participated in this study. Blood biomarkers were collected at rest, 5 min after, and 72 h after the 5mSRT to measure muscle damage (i.e., creatinine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase (ASAT), and alanine aminotransferase (ALAT)) and inflammation (i.e., C-reactive protein (CRP)). Best distance (BD), total distance (TD), fatigue index (FI), and percentage decrement (PD) during the 5mSRT were assessed. Perceived recovery (PRS) and delayed onset muscle soreness (DOMS) were recorded before, 5 min after, and 72 h after the 5mSRT; perceived exertion (RPE) was recorded before, during, and 72 h after the 5mSRT. Muscle damage biomarkers post 5mSRT showed a significant increase compared to pre 5mSRT ( p < 0.001) levels ((i.e., CK (190.6 ± 109.1 IU/L vs. 234.6 ± 113.7 IU/L), LDH (163.6 ± 35.1 IU/L vs. 209.9 ± 50.8 IU/L), ASAT (18.0 ± 4.4 IU/L vs. 21.7 ± 6.2 IU/L), and ALAT (10.2 ± 3.4 IU/L vs. 12.7 ± 3.8 IU/L)) and 72 h post 5mSRT ( p < 0.001) levels ((CK (125.3 ± 80.5 IU/L vs. 234.6 ± 113.7 IU/L), LDH (143.9 ± 36.6 IU/L vs. 209.9 ± 50.8 IU/L), ASAT (15.0 ± 4.7 IU/L vs. 21.7 ± 6.2 IU/L), and ALAT (8.6 ± 2.4 IU/L vs. 12.7 ± 3.8 IU/L)). CRP was also significantly higher post 5mSRT compared to pre 5mSRT (2.1 ± 2.5 mg/L vs. 2.8 ± 3.3 mg/L, p < 0.001) and 72 h post 5mSRT (1.4 ± 2.3 mg/L vs. 2.8 ± 3.3 mg/L, p < 0.001). Significant correlations were reported between (i) physical performance parameters (i.e., PD, FI, TD, and BD), and (ii) markers of muscle damage (i.e., CK, LDH, ASAT, and ALAT) and inflammation (i.e., CRP). Similarly, DOMS and RPE scores were significantly higher post 5mSRT compared to pre 5mSRT (2.4 ± 1.0UA vs. 6.7 ± 1.1UA and 2.1 ± 0.6 UA vs. 8.1 ± 0.6 UA, respectively p < 0.001) and 72 h post 5mSRT (1.9 ± 0.7 UA vs. 6.7 ± 1.1 UA and 1.5 ± 0.6 UA vs. 8.1 ± 0.6 UA, respectively p < 0.001). PRS scores were significantly lower post 5mSRT as compared to pre 5mSRT (6 ± 1 UA vs. 3 ± 1 UA, p < 0.001) and 72 h post 5mSRT (7 ± 1 UA vs. 3 ± 1 UA, p < 0.001). Significant correlations existed between (i) performance parameters (PD, FI, TD, and BD) and (ii) RPE, PRS, and DOMS. The 5mSRT increased biomarkers of muscle damage and inflammation, as well as the DOMS and RPE and reduced the PRS. Seventy-two hours was sufficient for fatigue recovery induced by the 5mSRT. PD is better than FI for the calculation of performance decrements during the 5mSRT to represent fatigue.

Keywords: repeated sprint; muscle damage; inflammation; fatigue; muscle soreness (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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