Venous Thromboembolism in Children: From Diagnosis to Management

Giuseppe Lassandro, Viviana Valeria Palmieri, Valentina Palladino, Anna Amoruso, Maria Felicia Faienza and Paola Giordano
Additional contact information
Giuseppe Lassandro: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy
Viviana Valeria Palmieri: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy
Valentina Palladino: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy
Anna Amoruso: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy
Maria Felicia Faienza: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy
Paola Giordano: Department of Biomedical Sciences and Human Oncology, Paediatric Section, University of Bari “A. Moro”, 701024 Bari, Italy

IJERPH, 2020, vol. 17, issue 14, 1-10

Abstract: Venous thromboembolism (VTE) in children is a rare occurrence, although in recent decades we have seen an increase due to several factors, such as the rise in survival of subjects with chronic conditions, the use of catheters, and the increased sensitivity of diagnostic tools. Besides inherited thrombophilia, acquired conditions such as cardiovascular diseases, infections, chronic disorders, obesity and malignancy are also common risk factors for paediatric VTE. The treatment of paediatric VTE consists of the use of heparins and/or vitamin K antagonists to prevent dissemination, embolization, and secondary VTE. Randomized clinical trials of direct oral anticoagulants in paediatric VTE are ongoing, with the aim to improve the compliance and the care of patients. We reviewed the physiological and pathological mechanisms underlying paediatric thrombosis and updated the current diagnosis and treatment options.

Keywords: thrombosis; paediatrics; risk factors; diagnosis; treatment (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/17/14/4993/pdf (application/pdf)
https://www.mdpi.com/1660-4601/17/14/4993/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:17:y:2020:i:14:p:4993-:d:383205

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().