The Effect of Bariatric Surgery on Weight Loss and Metabolic Changes in Adults with Obesity

Stanisław Głuszek, Arkadiusz Bociek, Edyta Suliga, Jarosław Matykiewicz, Magdalena Kołomańska, Piotr Bryk, Przemysław Znamirowski, Łukasz Nawacki, Martyna Głuszek-Osuch, Iwona Wawrzycka and Dorota Kozieł
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Stanisław Głuszek: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Arkadiusz Bociek: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Edyta Suliga: The Institute of Health Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Jarosław Matykiewicz: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Magdalena Kołomańska: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Piotr Bryk: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Przemysław Znamirowski: Clinic of General, Oncological and Endocrinological Surgery, Provincial Hospital in Kielce, 25-736 Kielce, Poland
Łukasz Nawacki: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Martyna Głuszek-Osuch: The Institute of Health Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Iwona Wawrzycka: The Institute of Medical Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland
Dorota Kozieł: The Institute of Health Sciences, Medical College, Jan Kochanowski University, 25-369 Kielce, Poland

IJERPH, 2020, vol. 17, issue 15, 1-11

Abstract: Methods of treating obesity, such as changes in lifestyle, physical activity, restrictive diets, and psychotherapy, are not sufficient. Currently, it is considered that in the case of patients who meet the eligibility criteria for surgery, the treatment of choice should be bariatric surgery. The aim of this study was to assess the weight loss and metabolic changes in a group of adults with obesity undergoing bariatric surgery. The study involved 163 patients whose body mass index (BMI) exceeded 40 or 35 kg/m 2 , concurrent with at least one metabolic sequelae. In 120 of the cases (74%), sleeve gastrectomy was used; in 35 (21%), gastric banding was used; and in 8 (5%), laparoscopic Roux-en-Y gastric bypass was used. Metabolic parameters such as total cholesterol, LDL-cholesterol (low-density lipoprotein cholesterol), HDL-cholesterol (high-density lipoprotein cholesterol), triglycerides, and glucose were measured preoperatively and postoperatively, as well as the creatinine, creatine kinase (CK-MB), and leptin activity. In patients undergoing bariatric surgery, a significant decrease in excess weight ( p < 0.001) was observed at all the analyzed time points, compared to the pre-surgery value. Weight loss after surgery was associated with a significant improvement in glycemia (109.6 ± 48.0 vs. 86.6 ± 7.9 mg/dL >24 months after surgery; p = 0.003), triglycerides (156.9 ± 79.6 vs. 112.7 ± 44.3 mg/dL >24 months after surgery; p = 0.043) and leptin (197.50 ± 257.3 vs. 75.98 ± 117.7 pg/mL 12 months after surgery; p = 0.0116) concentration. The results of the research confirm the thesis on the effectiveness of bariatric surgery in reducing excess body weight and improving metabolic parameters in patients with extreme obesity.

Keywords: sleeve gastrectomy (SG); gastric banding (GB); laparoscopic Roux-en-Y gastric bypass (LRYGB); weight loss; metabolic parameters (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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