Changes in Lipid Profile, Body Weight Variables and Cardiovascular Risk in Obese Patients Undergoing One-Anastomosis Gastric Bypass

Jose-Maria Jiménez, Miguel-Angel Carbajo, María López, María-José Cao, Jaime Rúiz-Tovar, Sara García and María-José Castro
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Jose-Maria Jiménez: Center of Excellence for the Study and Treatment of Diabetes and Obesity, 47004 Valladolid, Spain
Miguel-Angel Carbajo: Center of Excellence for the Study and Treatment of Diabetes and Obesity, 47004 Valladolid, Spain
María López: Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain
María-José Cao: Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain
Jaime Rúiz-Tovar: Center of Excellence for the Study and Treatment of Diabetes and Obesity, 47004 Valladolid, Spain
Sara García: Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain
María-José Castro: Center of Excellence for the Study and Treatment of Diabetes and Obesity, 47004 Valladolid, Spain

IJERPH, 2020, vol. 17, issue 16, 1-10

Abstract: Morbid obesity has a direct impact on the development of cardiovascular disease. One-anastomosis gastric bypass (OAGB) is an effective surgical technique for the control of body weight and the reduction of cardiovascular risk. This work examines the change in weight loss, lipid profile and cardiovascular risk in 100 patients (71 women, 29 men), mean age 42.61 ± 11.33 years at 3, 6, 9, 12, 18 and 24 months after OAGB. At 24 months post-surgery, mean body weight was significantly reduced compared to pre-operative values (116.75 ± 22.19 kg vs. 69.66 ± 13.07 kg), as were mean total cholesterol (201.86 ± 44.60 mg/dL vs. 172.99 ± 32.26 mg/dL), LDL (Low-Density Lipoprotein) cholesterol (126.90 ± 39.81 mg/dL vs. 96.28 ± 26.99 mg/dL), triglycerides (138.05 ± 78.45 mg/dL vs. 76.04 ± 30.34 mg/dL) and cardiovascular risk (total cholesterol/HDL (High-Density Lipoprotein) cholesterol: 4.32 ± 1.24 vs. 2.93 ± 0.71), while the mean HDL cholesterol concentration was significantly higher (49.09 ± 14.16 mg/dL vs. 61.98 ± 14.86 mg/dL) (all p < 0.001). In conclusion, OAGB surgery led to significant reductions in body weight, a significant improvement in the lipid profile, and a reduction in cardiovascular risk.

Keywords: morbid obesity; lipid profile; weight loss; one-anastomosis gastric bypass; cardiovascular risk (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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