Biomarkers of Exposure among USA Adult Hookah Users: Results from Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study (2013–2014)

Mark J. Travers, Cheryl Rivard, Eva Sharma, Sandra Retzky, Berran Yucesoy, Maciej L. Goniewicz, Cassandra A. Stanton, Jiping Chen, Priscilla Callahan-Lyon, Heather L. Kimmel, Baoyun Xia, Yuesong Wang, Connie S. Sosnoff, Víctor R. De Jesús, Benjamin C. Blount, Stephen S. Hecht and Andrew Hyland
Additional contact information
Mark J. Travers: Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA
Cheryl Rivard: Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA
Eva Sharma: Westat, Rockville, MD 20850, USA
Sandra Retzky: Food and Drug Administration, Center for Tobacco Products, Calverton, MD 20705, USA
Berran Yucesoy: Food and Drug Administration, Center for Tobacco Products, Calverton, MD 20705, USA
Maciej L. Goniewicz: Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA
Cassandra A. Stanton: Westat, Rockville, MD 20850, USA
Jiping Chen: Food and Drug Administration, Center for Tobacco Products, Calverton, MD 20705, USA
Priscilla Callahan-Lyon: Food and Drug Administration, Center for Tobacco Products, Calverton, MD 20705, USA
Heather L. Kimmel: National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
Baoyun Xia: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Yuesong Wang: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Connie S. Sosnoff: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Víctor R. De Jesús: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Benjamin C. Blount: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Stephen S. Hecht: Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
Andrew Hyland: Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA

IJERPH, 2020, vol. 17, issue 17, 1-16

Abstract: Hookah smoking has become common in the USA, especially among young adults. This study measured biomarkers of exposure to known tobacco product toxicants in a population-based sample of exclusive, established hookah users. Urinary biomarker data from 1753 adults in Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study were used to compare geometric mean concentrations of biomarkers of exposure in exclusive, established past 30-day hookah users to never users of tobacco. Geometric mean ratios were calculated comparing hookah user groups with never users adjusting for age, sex, race/ethnicity, education, past 30-day marijuana use, secondhand smoke exposure and creatinine. Past 30-day hookah users ( n = 98) had 10.6 times the urinary cotinine level of never tobacco users. Compared to never tobacco users, past 30-day hookah users had 2.3 times the level of the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 1.3 times higher polycyclic aromatic hydrocarbons (PAHs) 3-hydroxyfluorene and 1-hydroxypyrene, 1.8 times higher levels of acrylonitrile, 1.3 times higher levels of acrylamide, and 1.2 times higher levels of acrolein exposure. These data indicate that hookah use is a significant source of exposure to nicotine, carcinogens, and respiratory toxicants.

Keywords: hookah 1; biomarkers 2; tobacco 3 (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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