Quality of Life Changes in Acute Coronary Syndromes Patients: A Systematic Review and Meta-Analysis

Billingsley Kaambwa, Hailay Abrha Gesesew, Matthew Horsfall and Derek Chew
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Billingsley Kaambwa: College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
Hailay Abrha Gesesew: College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
Matthew Horsfall: College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
Derek Chew: College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia

IJERPH, 2020, vol. 17, issue 18, 1-28

Abstract: There is little up-to-date evidence about changes in quality of life following treatment for acute coronary syndrome (ACS) patients. The main aim of this review was to assess the changes in QoL in ACS patients after treatment. We undertook a systematic review and meta-analysis of quantitative studies. The search included studies that described the change of QoL of ACS patients after receiving treatment options such as percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) and medical therapy (MT). We synthesized findings using content analysis and pooled the estimates using meta-analysis. We used the PRISMA guidelines to select and appraise the studies and report the findings. Twenty-nine (29) articles were included in the review. We found a significant improvement of QoL in ACS patients after receiving treatment. Particularly, the meta-analytic association found that the mean QoL of patients diagnosed with ACS was higher after receiving treatment compared to baseline (overall pooled mean difference = 31.88; 95% CI = 31.64–52.11, I 2 = 98) with patients on PCI having slightly lower QoL gains (pooled mean difference = 30.22; 95% CI = 29.9–30.53, I 2 = 0%) compared to those on CABG (pooled mean difference = 34.01; 95% CI = 33.66–34.37, I 2 = 0%). The review confirmed that QoL of ACS patients improved after receiving treatment therapies although varied by the treatment options and patients’ preferences. This suggests the need to perform further study on the QoL, patient preferences and physicians’ decision to prescription of treatment options.

Keywords: quality of life; percutaneous coronary intervention; coronary artery bypass grafting; physician therapy; acute coronary syndrome; systematic review (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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