Outcome and Subsequent Pregnancy after Fertility-Sparing Surgery of Early-Stage Cervical Cancers

Chia-Yi Lee, Yu-Li Chen, Ying-Cheng Chiang, Ching-Yu Cheng, Yen-Ling Lai, Yi-Jou Tai, Heng-Cheng Hsu, Hsiao-Lin Hwa and Wen-Fang Cheng
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Chia-Yi Lee: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Yu-Li Chen: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Ying-Cheng Chiang: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Ching-Yu Cheng: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Yen-Ling Lai: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Yi-Jou Tai: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Heng-Cheng Hsu: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Hsiao-Lin Hwa: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Wen-Fang Cheng: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100, Taiwan

IJERPH, 2020, vol. 17, issue 19, 1-11

Abstract: We aimed to investigate the outcomes and subsequent pregnancies of early-stage cervical cancer patients who received conservative fertility-sparing surgery. Women with early-stage cervical cancer who underwent conservative or fertility-sparing surgery in a tertiary medical center were reviewed from 2004 to 2017. Each patient’s clinicopathologic characteristics, adjuvant therapy, subsequent pregnancy, and outcome were recorded. There were 32 women recruited, including 12 stage IA1 patients and 20 stage IB1 patients. Twenty-two patients received conization/LEEP and the other 10 patients received radical trachelectomy. Two patients did not complete the definite treatment after fertility-sparing surgery. There were 11 women who had subsequent pregnancies and nine had at least one live birth. The live birth rate was 73.3% (11/15). We conclude that patients with early-stage cervical cancer who undergo fertility-sparing surgery can have a successful pregnancy and delivery. However, patients must receive a detailed consultation before surgery and undergo definitive treatment, if indicated, and regular postoperative surveillance.

Keywords: cervical cancer; fertility-sparing surgery; conization; radical trachelectomy; pregnancy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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