Augmented Hemodynamic Responses in Obese Young Men during Dynamic Exercise: Role of the Muscle Metaboreflex

Byung-Sun Lee, Kyung-Ae Kim, Jong-Kyung Kim and Hosung Nho
Additional contact information
Byung-Sun Lee: Graduate School of Physical Education, Kyung Hee University, Seocheon-dong, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Korea
Kyung-Ae Kim: Wellness IT Company Limited, 38, Teheran-ro 19-gil, Gangnam-gu, Seoul 06131, Korea
Jong-Kyung Kim: Wellness IT Company Limited, 38, Teheran-ro 19-gil, Gangnam-gu, Seoul 06131, Korea
Hosung Nho: Wellness IT Company Limited, 38, Teheran-ro 19-gil, Gangnam-gu, Seoul 06131, Korea

IJERPH, 2020, vol. 17, issue 19, 1-14

Abstract: Studies found that cardiovascular responses to exercise are enhanced in individuals with obesity and are associated with a greater cardiac output (CO) response compared to normal weight controls. However, the mechanisms underlying these altered responses during dynamic exercise are not clear. We investigated whether the cardiovascular responses mediated by the muscle metaboreflex (MMR) activation are augmented in obese men during both static and dynamic exercise. Twenty males (10 obese (OG) and 10 non-obese (NOG)) were studied. Changes in CO, mean arterial pressure (MAP), and total vascular conductance (TVC) were compared between the two groups during dynamic handgrip exercise (DHE), post-exercise muscular ischemia (PEMI), and dynamic exercise corresponding to 40%, 60% and 80% workloads. Subjects completed 2 min of DHE at 30% of MVC, followed by 2 min of PEMI. MAP, CO, and TVC responses to DHE and dynamic exercise were significantly higher in OG, whereas there were no differences during PEMI. Increases in CO and MAP during mild to heavy dynamic exercise were seen in both groups, but the changes in these variables were greater in the OG. There were no significant differences in TVC between the two groups. Compared to NOG, the augmented blood pressure response to DHE and dynamic exercise in OG was associated with a greater increase in CO. Thus, the augmented CO and MAP responses were not associated with the activation of the MMR. Consequently, additional factors specific to obesity, such as the mechanoreflex, may have been involved.

Keywords: obese young men; hemodynamic response; dynamic exercise; post-exercise muscular ischemia; total vascular conductance (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/17/19/7321/pdf (application/pdf)
https://www.mdpi.com/1660-4601/17/19/7321/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:17:y:2020:i:19:p:7321-:d:424608

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().