Sleep Regularity Index in Patients with Alcohol Dependence: Daytime Napping and Mood Disorders as Correlates of Interest

Alyssa T. Brooks, Shravya Raju, Jennifer J. Barb, Narjis Kazmi, Subhajit Chakravorty, Michael Krumlauf and Gwenyth R. Wallen
Additional contact information
Alyssa T. Brooks: National Institutes of Health Clinical Center, 10 Center Drive, Bethesda, MD 20892, USA
Shravya Raju: National Institutes of Health Clinical Center, 10 Center Drive, Bethesda, MD 20892, USA
Jennifer J. Barb: Mathematical and Statistical Computing Lab/CIT/NIH, 12 South Drive Bldg 12A Room 2001, Bethesda, MD 20892, USA
Narjis Kazmi: National Institutes of Health Clinical Center, 10 Center Drive, Bethesda, MD 20892, USA
Subhajit Chakravorty: Corporal Michael J. Crescenz VA Medical Center, Perelman School of Medicine, MIRECC, 2nd Floor, Mail stop 116, 3900 Woodland Avenue, Philadelphia, PA 19104, USA
Michael Krumlauf: National Institutes of Health Clinical Center, 10 Center Drive, Bethesda, MD 20892, USA
Gwenyth R. Wallen: National Institutes of Health Clinical Center, 10 Center Drive, Bethesda, MD 20892, USA

IJERPH, 2020, vol. 17, issue 1, 1-16

Abstract: Alcohol use disorder (AUD) is often accompanied by comorbid conditions, including sleep disturbances related to sleep regularity and timing. The Sleep Regularity Index (SRI) is a novel measure that assesses the probability that an individual is awake (vs. asleep) at any two time points 24 h apart. We calculated actigraphy-based SRI on 124 participants with alcohol dependence to capture the effects of changes in sleep timing and duration among patients enrolled in an inpatient alcohol treatment program. During the course of the study, the mean SRI increased between weeks 1 and 3 (75.4 to 77.8), thus indicating slightly improved sleep quality and regularity during alcohol treatment. Individuals within the bottom quartile of SRI scores at week 1 improved significantly over time. Average total SRI for individuals with no mood disorders was slightly higher than that for individuals with one or more mood disorders. Increased SRI scores were associated with lower total nap duration from week 1 to week 3. Increased SRI scores were associated with decreased mental/physical exhaustion scores from week 1 to week 3. The SRI could be a target for assessment/intervention in certain sub-groups of individuals undergoing inpatient treatment for AUD.

Keywords: alcohol use disorder; sleep disturbance; insomnia; sleep regularity; mood disorder; substance use disorder (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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