Health-Related Quality of Life and Physical Function in Individuals with Parkinson’s Disease after a Multidisciplinary Rehabilitation Regimen—A Prospective Cohort Feasibility Study

Christina Nielsen, Volkert Siersma, Emma Ghaziani, Nina Beyer, S. Peter Magnusson and Christian Couppé
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Christina Nielsen: Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark
Volkert Siersma: Research Unit and Department of General Practice, Institute of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark
Emma Ghaziani: Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark
Nina Beyer: Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark
S. Peter Magnusson: Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark
Christian Couppé: Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark

IJERPH, 2020, vol. 17, issue 20, 1-13

Abstract: Parkinson’s disease (PD) is a neurodegenerative disease and a multidisciplinary approach to rehabilitation has been suggested as the best clinical practice. However, very few studies have investigated the long-term effects of a multidisciplinary rehabilitation approach, particularly regarding whether this can slow the progression of PD. The purpose was to investigate the short- and long-term effect of a 2-week multidisciplinary rehabilitation regimen on the PD-related decline in health-related quality of life (HRQOL), mobility, and muscle function. Individuals with PD (IPD) participated in a 2-week inpatient multidisciplinary rehabilitation regimen that focused on improving HRQOL, mobility, and muscle function. Data from the primary outcome: HRQOL (Parkinson’s Disease Questionnaire 39, PDQ-39), secondary outcomes: handgrip strength, Timed-up and Go (TUG), Hospital Anxiety and Depression Scale (HADS), and Falls Efficacy Scale-International (FES-I) were compared at pre-visitation, before and after the 2-week regimen, and again at 4 and 10 months follow-up. In total, 224 patients with PD were included. There were short-term improvements in all outcomes. PDQ-39 was maintained at the same level as pre-visitation after 10 months follow-up. A 2-week multidisciplinary rehabilitation regimen improved short-term mobility, muscle function, and HRQOL in individuals with Parkinson’s disease. HRQOL was maintained after 10 months demonstrating long-term effects.

Keywords: multidisciplinary rehabilitation; health-related quality of life; physical function; Parkinson’s disease (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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