Epidemiology of Rotavirus Gastroenteritis and Rotavirus-Associated Benign Convulsions with Mild Gastroenteritis after the Introduction of Rotavirus Vaccines in South Korea: Nationwide Data from the Health Insurance Review and Assessment Service
Dong Hyun Kim,
Yeong Seok Lee,
Dong Jun Ha,
Min Jun Chun and
Young Se Kwon
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Dong Hyun Kim: Department of Pediatrics, School of Medicine, Inha University, Incheon 22332, Korea
Yeong Seok Lee: Department of Pediatrics, School of Medicine, Inha University, Incheon 22332, Korea
Dong Jun Ha: Department of Pediatrics, School of Medicine, Inha University, Incheon 22332, Korea
Min Jun Chun: Department of Pediatrics, School of Medicine, Inha University, Incheon 22332, Korea
Young Se Kwon: Department of Pediatrics, School of Medicine, Inha University, Incheon 22332, Korea
IJERPH, 2020, vol. 17, issue 22, 1-10
Abstract:
Using nationwide data from the Health Insurance Review and Assessment service, we assessed the impact of rotavirus vaccines, introduced in South Korea, in 2007, on changes in the prevalence of factors (age, sex, and geographic location) associated with rotavirus gastroenteritis (RVGE) and rotavirus-associated benign convulsions with mild gastroenteritis (RaCwG). We analyzed health records of children younger than 3 years who visited clinical facilities and were diagnosed with RVGE or RaCwG between 2007 and 2019. The annual mid-year population (MYP) was obtained from the Korean Statistical Information Service. The annual prevalence of RVGE, RaCwG and associated factors were statistically analyzed. Overall, 219,686, and 4032, children were confirmed to have RVGE and RaCwG, respectively. Although the annual prevalence of RVGE decreased significantly, that of RaCwG did not. The annual ratio of RaCwG to RVGE was significantly high. Compared to the prevalence of RVGE, the prevalence of RaCwG was significantly lower in rural areas. The age of RaCwG patients was significantly lower than that of the MYP and that of RVGE patients. The decrease in the number of RaCwG patients after rotavirus vaccination was not as pronounced as the decrease in the number of RVGE patients.
Keywords: rotavirus vaccines; rotavirus infections; seizure (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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