Association between SSNHL and Thyroid Diseases

So Young Kim, Young Shin Song, Jee Hye Wee, Chanyang Min, Dae Myoung Yoo and Hyo Geun Choi
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So Young Kim: CHA Bundang Medical Center, Department of Otorhinolaryngology-Head & Neck Surgery, CHA University, Seongnam 13496, Korea
Young Shin Song: CHA Bundang Medical Center, Department of Internal Medicine, CHA University, Seongnam 13496, Korea
Jee Hye Wee: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea
Chanyang Min: Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea
Dae Myoung Yoo: Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea
Hyo Geun Choi: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea

IJERPH, 2020, vol. 17, issue 22, 1-11

Abstract: The association between thyroid disease and sudden sensorineural hearing loss (SSNHL) has not been evaluated. We investigated the association of goiter, hypothyroidism, thyroiditis, and hyperthyroidism with sudden sensorineural hearing loss (SSNHL). Data from the Korean National Health Insurance Service-Health Screening Cohort were used. The 8658 SSNHL patients were matched in a 1:4 ratio with 34,632 controls for age, sex, and region of residence. Histories of goiter, hypothyroidism, thyroiditis, hyperthyroidism, and Levothyroxine medication were explored as possible factors influencing SSNHL development. Associations were estimated using conditional logistic regression analyses, adjusted for Levothyroxine medication use. Subgroup analyses were conducted according to age, sex, income, and region of residence. SSNHL patients had a higher rate of goiter occurrence (4.4% vs. 3.7 %, p = 0.001) and hypothyroidism (4.0% vs. 3.2 %, p < 0.001) than controls. Goiter and hypothyroidism were positively associated with SSNHL (adjusted OR =1.14 (95% CI =1.01–1.28), p = 0.043 for goiter and 1.17 (95% CI =1.03–1.33), p = 0.016 for hypothyroidism). In subgroup analyses, hypothyroidism or goiter was more prevalent in SSNHL patients than in controls. Lower-income subgroups showed associations of hypothyroidism and goiter with SSNHL. SSNHL patients were more likely to have goiter and hypothyroidism than normal individuals.

Keywords: hearing loss; sudden; hyperthyroidism; cohort Studies; case-control studies (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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