The ECETOC-Targeted Risk Assessment Tool for Worker Exposure Estimation in REACH Registration Dossiers of Chemical Substances—Current Developments

Jan Urbanus, Oliver Henschel, Qiang Li, Dave Marsh, Chris Money, Dook Noij, Paul van de Sandt, Joost van Rooij and Matthias Wormuth
Additional contact information
Jan Urbanus: Shell Health Risk Science Team, Belgian Shell N.V., B-1000 Brussels, Belgium
Oliver Henschel: Corporate Health Management, BASF SE, 67056 Ludwigshafen am Rhein, Germany
Qiang Li: Clariant Produkte (Deutschland) GmbH, 65843 Sulzbach am Taunus, Germany
Dave Marsh: ExxonMobil Biomedical Sciences Inc, ExxonMobil, Leatherhead KT22 8UX, UK
Chris Money: Cynara Consulting, Brockenhurst SO42 7RX, UK
Dook Noij: In Personal Capacity, Formerly Dow Global Industrial Hygiene Expertise Centre, 4531 EB Terneuzen, The Netherlands
Paul van de Sandt: Shell Health Risk Science Team, Shell International B.V., 2596 HR The Hague, The Netherlands
Joost van Rooij: Caesar Consult, 6503 CB Nijmegen, The Netherlands
Matthias Wormuth: Syngenta Crop Protection AG, 4058 Basel, Switzerland

IJERPH, 2020, vol. 17, issue 22, 1-9

Abstract: (1) Background: The ECETOC Targeted Risk Assessment (TRA) tool is widely used for estimation of worker exposure levels in the development of dossiers for REACH registration of manufactured or imported chemical substances in Europe. A number of studies have been published since 2010 in which the exposure estimates of the tool are compared with workplace exposure measurement results and in some instances an underestimation of exposure was reported. The quality and results of these studies are being reviewed by ECETOC. (2) Methods: Original exposure measurement data from published comparison studies for which six or more data points were available for each workplace scenario and a TRA estimate had been developed to create a curated database to examine under what conditions and for which applications the tool is valid or may need adaptation. (3) Results: The published studies have been reviewed for completeness and clarity and TRA estimates have been constructed based on the available information, following a set of rules. The full review findings are expected to be available in the course of 2021. (4) Conclusions: The ECETOC TRA tool developers periodically review the validity and limitations of their tool, in line with international recommendations.

Keywords: chemicals; exposure modelling; occupational exposure; chemical regulation (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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