Alcohol Use Disorders and Increased Risk of Adverse Birth Complications and Outcomes: An 11-Year Nationwide Cohort Study

Sarah Soyeon Oh, Yongho Jee, Eun-Cheol Park and Young Ju Kim
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Sarah Soyeon Oh: Fetal Alcohol Syndrome Prevention Center, Ewha Mokdong Hospital, Ewha Womans University, Seoul 07985, Korea
Yongho Jee: Fetal Alcohol Syndrome Prevention Center, Ewha Mokdong Hospital, Ewha Womans University, Seoul 07985, Korea
Eun-Cheol Park: Department of Preventive Medicine, Yonsei University, Seoul 03722, Korea
Young Ju Kim: Fetal Alcohol Syndrome Prevention Center, Ewha Mokdong Hospital, Ewha Womans University, Seoul 07985, Korea

IJERPH, 2020, vol. 17, issue 22, 1-10

Abstract: For women who suffer from Alcohol Use Disorders (AUDs), the use of alcohol before and/or during pregnancy may result in various birth complications, including miscarriage, stillbirth, or preterm delivery. Thus, this study aimed to explore whether Alcohol Use Disorders (AUDs) are associated with increased risk of adverse birth complications and outcomes. A total of 76,799 deliveries between 2003 and 2013 in the Korean National Health Insurance Service National Sample Cohort (NHIS-NSC) were analyzed. Women with an AUD diagnosis preceding delivery were identified as individuals with alcohol dependence. A multivariate Cox proportional hazards model was used to estimate the hazard ratio of adverse birth complications and outcomes associated with alcohol dependence. Diagnosis of an AUD was associated with increased risk of adverse birth complications (Hazard Ratio [HR]: 1.15, 95% CI: 1.01–1.31, p = 0.0302). This was especially the case for women whose AUD diagnosis was in the same year as their delivery (HR: 1.53, 95% CI: 1.24–1.88, p < 0.0001). AUDs were associated with increased risk of adverse birth outcomes, especially when prevalent in the same year as a woman’s delivery. Our study confirms that the monitoring of expecting women with a diagnosis of alcohol-related problems may be useful in preventing adverse birth complications.

Keywords: preterm birth; prenatal alcohol exposure; birth complications (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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