The Toxicity Exerted by the Antibiotic Sulfadiazine on the Growth of Soil Bacterial Communities May Increase over Time

Vanesa Santás-Miguel, Laura Rodríguez-González, Avelino Núñez-Delgado, Montserrat Díaz-Raviña, Manuel Arias-Estévez and David Fernández-Calviño
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Vanesa Santás-Miguel: Área de Edafoloxía e Química Agrícola, Facultade de Ciencias, Universidade de Vigo, 32004 Ourense, Galiza, Spain
Laura Rodríguez-González: Área de Edafoloxía e Química Agrícola, Facultade de Ciencias, Universidade de Vigo, 32004 Ourense, Galiza, Spain
Avelino Núñez-Delgado: Departamento de Edafoloxía e Química Agrícola, Escola Politécnica Superior de Enxeñaría, Universidade de Santiago de Compostela, 15705 Lugo, Galicia, Spain
Montserrat Díaz-Raviña: Departamento de Bioquímica del Suelo, Instituto de Investigaciones Agrobiologicas de Galicia (IIAG/CSIC), 15705 Santiago de Compostela, Galicia, Spain
Manuel Arias-Estévez: Área de Edafoloxía e Química Agrícola, Facultade de Ciencias, Universidade de Vigo, 32004 Ourense, Galiza, Spain
David Fernández-Calviño: Área de Edafoloxía e Química Agrícola, Facultade de Ciencias, Universidade de Vigo, 32004 Ourense, Galiza, Spain

IJERPH, 2020, vol. 17, issue 23, 1-10

Abstract: The toxicity exerted by the antibiotic sulfadiazine on the growth of soil bacterial communities was studied in two agricultural soils for a period of 100 days. In the short-term (2 days of incubation), the effect of sulfadiazine on bacterial growth was low (no inhibition or inhibition <32% for a dose of 2000 mg·kg −1 ). However, sulfadiazine toxicity increased with time, achieving values of 40% inhibition, affecting bacterial growth in both soils after 100 days of incubation. These results, which were here observed for the first time for any antibiotic in soil samples, suggest that long-term experiments would be required for performing an adequate antibiotics risk assessment, as short-term experiments may underestimate toxicity effects.

Keywords: leucine incorporation; risk assessment; sulfonamide; veterinary; microbial community (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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