Chemical Characterization and Quantification of Titanium Dioxide Nanoparticles (TiO 2 -NPs) in Seafood by Single-Particle ICP-MS: Assessment of Dietary Exposure

Alfina Grasso, Margherita Ferrante, Pietro Zuccarello, Tommaso Filippini, Giovanni Arena, Maria Fiore, Antonio Cristaldi, Gea Oliveri Conti and Chiara Copat
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Alfina Grasso: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Margherita Ferrante: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Pietro Zuccarello: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Tommaso Filippini: Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, Section of Public Health, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy
Giovanni Arena: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Maria Fiore: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Antonio Cristaldi: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Gea Oliveri Conti: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy
Chiara Copat: Department of Medical, Surgical and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy

IJERPH, 2020, vol. 17, issue 24, 1-15

Abstract: The significant increase in the production and variety of nanoparticles (NPs) has led to their release into the environment, especially into the marine environment. Titanium dioxide nanoparticles (TiO 2 -NPs) are used in different industrial sectors, from the food industry to several consumer and household products. Since the aquatic environment is highly sensitive to contamination by TiO 2 -NPs, this work aimed to give a preliminary assessment of the contamination of packaged seafood, where the food additive TiO 2 (E171) is not to be intentionally added. This allowed providing a chemical characterization and quantification of TiO 2 -NPs in processed canned fish products belonging to different trophic positions of the pelagic compartment and in canned clam. The new emerging technique called single-particle inductively coupled plasma mass spectrometry ( sp ICP-MS) was applied, which allows the determination of nanoparticle number-based concentration, as well as the dissolved titanium. This study highlights how processed food, where the pigment E171 was not intentionally added, contains TiO 2 in its nanoparticle form, as well as dissolved titanium. Processed clam represented the seafood with the highest content of TiO 2 -NPs. In pelagic fish species, we found progressively higher levels and smaller sizes of TiO 2 -NPs from smaller to larger fish. Our results highlight the importance of planning the characterization and quantification of TiO 2 -NPs in food both processed and not, as well as where the pigment E171 is intentionally added and not, as it is not the only source of TiO 2 -NPs. This result represents a solid step toward being able to estimate the real level of dietary exposure to TiO 2 -NPs for the general population and the related health risks.

Keywords: titanium dioxide; nanoparticle; sp ICP-MS; processed food; dietary intake; E171 (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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