Environmental Exposure of Arsenic in Groundwater Associated to Carcinogenic Risk in Underweight Children Exposed to Fluorides

Nelly Molina-Frechero, Martina Nevarez-Rascón, Omar Tremillo-Maldonado, Marcela Vergara-Onofre, Rey Gutiérrez-Tolentino, Enrique Gaona, Enrique Castañeda, Lizet Jarquin-Yañez and Ronell Bologna-Molina
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Nelly Molina-Frechero: Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico
Martina Nevarez-Rascón: Faculty of Dentistry, Universidad Autónoma de Chihuahua, Chihuahua 31000, Mexico
Omar Tremillo-Maldonado: Research Department, Faculty of Dentistry, Universidad Juárez del Estado de Durango, Durango 34000, Mexico
Marcela Vergara-Onofre: Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico
Rey Gutiérrez-Tolentino: Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico
Enrique Gaona: Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico
Enrique Castañeda: Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico
Lizet Jarquin-Yañez: Center of Applied Research in Environment and Health, CIACYT, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78120, Mexico
Ronell Bologna-Molina: Research Department, Faculty of Dentistry, Universidad Juárez del Estado de Durango, Durango 34000, Mexico

IJERPH, 2020, vol. 17, issue 3, 1-10

Abstract: Background: The purpose of this study was to determine the concentration of inorganic arsenic (As) in the potable water available to the population to be able to estimate the non-carcinogenic risks for underweight children and the carcinogenic risk for adults exposed to As intake who live in the Mezquital municipality, Durango, Mexico. Methods: The As content was quantifed in the water supply sources for human use and its intake was estimated in Mezquital population, southern Durango. With the data obtained, the hazard quotient (HQ) was calculated to determine the non-carcinogenic risk to develop chronic systemic effects in underweight children. The Environmental Protection Agency (EPA) reference health values estimating As exposure risk are from 0.0003 mg/kg/day (non-carcinogenic) to 1.5 mg/kg/day (carcinogenic risk). Results: The analyzed waters presented as concentrations that varied from 0.3 to 10.2 µg/L, with a mean of 7.35 µg/L (CI 95% 6.27–8.38). The exposure dose was 0.4 to 1.36, and the HQ was 1.90 to 6.48 mg/kg/day, the estimated carcinogenic risk from adults varied from 1.28 to 4.37E −4 , with values of 3.74–4.37E −4 mg/kg/day in central area. Conclusions: The children are at risk to develop chronic systemic effects due to ingestion of As from water.

Keywords: arsenic; exposure dose; hazard quotient; non-carcinogenic; carcinogenic risk (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:17:y:2020:i:3:p:724-:d:312174

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