Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training

Antonello Sica, Paola Vitiello, Andrea Ronchi, Beniamino Casale, Armando Calogero, Evangelista Sagnelli, Gilca Costa Nachtigal, Teresa Troiani, Renato Franco, Giuseppe Argenziano, Elvira Moscarella and Caterina Sagnelli
Additional contact information
Antonello Sica: Department of Precision Medicine, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Paola Vitiello: Dermatology Unit, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Andrea Ronchi: Department of Mental Health and Preventive, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Beniamino Casale: Department of Pneumology and Tisiology, AO Dei Colli—V. Monaldi, 80130 Naples, Italy
Armando Calogero: Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy
Evangelista Sagnelli: Department of Mental Health and Preventive, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Gilca Costa Nachtigal: Department of Clinical Medicine, Faculty of Medicine at UFPel—Federal University of Pelotas, 1160 Centro, Pelotas, Brazil
Teresa Troiani: Department of Precision Medicine, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Renato Franco: Department of Mental Health and Preventive, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Giuseppe Argenziano: Dermatology Unit, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Elvira Moscarella: Dermatology Unit, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
Caterina Sagnelli: Department of Mental Health and Preventive, University of Campania Luigi Vanvitelli, 80131 Naples, Italy

IJERPH, 2020, vol. 17, issue 3, 1-10

Abstract: Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion.

Keywords: cutaneous lymphoma in the elderly; skin tumors; T-cell lymphomas; sport activity training (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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