Epigenetic Biomarkers for Environmental Exposures and Personalized Breast Cancer Prevention

Hannah Lui Park
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Hannah Lui Park: Department of Epidemiology, UC Irvine School of Medicine, Irvine, CA 92617, USA

IJERPH, 2020, vol. 17, issue 4, 1-18

Abstract: Environmental and lifestyle factors are believed to account for >80% of breast cancers; however, it is not well understood how and when these factors affect risk and which exposed individuals will actually develop the disease. While alcohol consumption, obesity, and hormone therapy are some known risk factors for breast cancer, other exposures associated with breast cancer risk have not yet been identified or well characterized. In this paper, it is proposed that the identification of blood epigenetic markers for personal, in utero, and ancestral environmental exposures can help researchers better understand known and potential relationships between exposures and breast cancer risk and may enable personalized prevention strategies.

Keywords: breast cancer; environmental exposures; lifestyle factors; epigenetics; DNA methylation; transgenerational inheritance (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:17:y:2020:i:4:p:1181-:d:319919

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