Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

Shih-Bin Su, Hsiao-Liang Chang and Kow-Tong Chen
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Shih-Bin Su: Department of Occupational Medicine, Chi-Mei Medical Center, Tainan 710, Taiwan
Hsiao-Liang Chang: Department of Surveillance, Centers for Disease Control, Taipei 100, Taiwan
Kow-Tong Chen: Department of Occupational Medicine, Tainan Municipal Hospital (managed by Show Chwan Medical Care Corporation), Tainan 701, Taiwan

IJERPH, 2020, vol. 17, issue 5, 1-15

Abstract: Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words “mumps” and “epidemiology”, “pathogenesis” or “vaccine” in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities.

Keywords: mumps; epidemiology; pathogenesis; vaccine (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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