Efficacy of Sea Salt-Based Mouthwash and Xylitol in Improving Oral Hygiene among Adolescent Population: A Pilot Study

Andrea Ballini, Stefania Cantore, Luca Signorini, Rajiv Saini, Salvatore Scacco, Antonio Gnoni, Alessio Danilo Inchingolo, Danila De Vito, Luigi Santacroce, Francesco Inchingolo and Gianna Dipalma
Additional contact information
Andrea Ballini: Department of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “Ernesto Quagliariello”, University of Bari Aldo Moro, 70125 Bari, Italy
Stefania Cantore: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Luca Signorini: Dental School, Unicamillus University, 00131 Rome, Italy
Rajiv Saini: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Salvatore Scacco: Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy
Antonio Gnoni: Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy
Alessio Danilo Inchingolo: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Danila De Vito: Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy
Luigi Santacroce: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Francesco Inchingolo: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Gianna Dipalma: Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy

IJERPH, 2020, vol. 18, issue 1, 1-10

Abstract: The scientific community has definitely demonstrated the importance of the use of mouthwash in daily oral hygiene. In our pilot study, we tested the effectiveness of a novel mouth rinse containing sea salt, xylitol, and lysozyme. Streptococcus mutans (S. mutans) growth, and plaque index in adolescent patients aged 14–17 years, were observed. The bacterial load was investigated by in vitro microbiological analysis; the plaque index was assessed through the O’Leary’s Plaque Control Record (PCR). The study has shown that the use of a sea salt-based mouthwash in daily oral hygiene reduces the bacterial levels of S. mutans ( p < 0.01) linked to the combined action of xylitol and lysozyme, together with the action of sea salt. Our preliminary data confirm and improve the main results reported in the scientific literature on the importance of the use of xylitol, lysozyme, and sea salt in oral health.

Keywords: xylitol; sea salt; lysozyme; plaque index; oral health; Streptococcus mutans; clinical microbiology (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2020
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/1/44/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/1/44/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2020:i:1:p:44-:d:467063

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().