Recovery-Stress Response of Blood-Based Biomarkers

Sebastian Hacker, Thomas Reichel, Anne Hecksteden, Christopher Weyh, Kristina Gebhardt, Mark Pfeiffer, Alexander Ferrauti, Michael Kellmann, Tim Meyer and Karsten Krüger
Additional contact information
Sebastian Hacker: Department of Exercise Physiology and Sports Therapy, Institute of Sport Science, Justus-Liebig-University Gießen, 35394 Gießen, Germany
Thomas Reichel: Department of Exercise Physiology and Sports Therapy, Institute of Sport Science, Justus-Liebig-University Gießen, 35394 Gießen, Germany
Anne Hecksteden: Institute of Sports and Preventive Medicine, Saarland University, 66123 Saarbrücken, Germany
Christopher Weyh: Department of Exercise Physiology and Sports Therapy, Institute of Sport Science, Justus-Liebig-University Gießen, 35394 Gießen, Germany
Kristina Gebhardt: Department of Exercise Physiology and Sports Therapy, Institute of Sport Science, Justus-Liebig-University Gießen, 35394 Gießen, Germany
Mark Pfeiffer: Institute of Sport Science, Johannes Gutenberg University Mainz, 55128 Mainz, Germany
Alexander Ferrauti: Department of Training & Exercise Science, Faculty of Sport Science, Ruhr University Bochum, 44801 Bochum, Germany
Michael Kellmann: Unit of Sport Psychology, Faculty of Sport Science, Ruhr University Bochum, 44801 Bochum, Germany
Tim Meyer: Institute of Sports and Preventive Medicine, Saarland University, 66123 Saarbrücken, Germany
Karsten Krüger: Department of Exercise Physiology and Sports Therapy, Institute of Sport Science, Justus-Liebig-University Gießen, 35394 Gießen, Germany

IJERPH, 2021, vol. 18, issue 11, 1-12

Abstract: The purpose of this study was to investigate blood-based biomarkers and their regulation with regard to different recovery-stress states. A total of 35 male elite athletes (13 badminton, 22 soccer players) were recruited, and two venous blood samples were taken: one in a ‘recovered’ state (REC) after a minimum of one-day rest from exercise and another one in a ‘non-recovered’ state (NOR) after a habitual loading microcycle. Overall, 23 blood-based biomarkers of different physiologic domains, which address inflammation, muscle damage, and tissue repair, were analyzed by Luminex assays. Across all athletes, only creatine kinase (CK), interleukin (IL-) 6, and IL-17A showed higher concentrations at NOR compared to REC time points. In badminton players, higher levels of CK and IL-17A at NOR were found. In contrast, a higher value for S100 calcium-binding protein A8 (S100A8) at REC was found in badminton players. Similar differences were found for BDNF in soccer players. Soccer players also showed increased levels of CK, and IL-6 at NOR compared to REC state. Several molecular markers were shown to be responsive to differing recovery-stress states, but their suitability as biomarkers in training must be further validated.

Keywords: cytokines; muscle damage; chemokines; badminton; soccer; monitoring (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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