Cytogenetic, Serum Liver Enzymes and Liver Cell Pathology of the Hampala Barb Fish (Hampala macrolepidota ) Affected by Toxic Elements in the Contaminated Nam Kok River near the Sepon Gold-Copper Mine, Lao PDR

Latsamy Soulivongsa, Bundit Tengjaroenkul, Isara Patawang and Lamyai Neeratanaphan
Additional contact information
Latsamy Soulivongsa: Toxic Substances, Microorganisms and Feed Additives in Livestock and Aquatic Animals for Food Safety Research Program, Khon Kaen University, Khon Kaen 40002, Thailand
Bundit Tengjaroenkul: Toxic Substances, Microorganisms and Feed Additives in Livestock and Aquatic Animals for Food Safety Research Program, Khon Kaen University, Khon Kaen 40002, Thailand
Isara Patawang: Research Center in Bioresources for Agriculture, Industry and Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
Lamyai Neeratanaphan: Division of Environmental Science, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand

IJERPH, 2021, vol. 18, issue 11, 1-16

Abstract: This study aimed to determine toxic element concentrations in aquatic environments, including water and sediment, and in the Hampala macrolepidota fish, and to evaluate chromosome abnormalities, serum liver enzyme changes and liver histopathological alterations in H. macrolepidota from the Nam Kok River near the Sepon gold-copper mine, Lao People’s Democratic Republic, as compared with a control area without mining activity. The results revealed significant differences ( p < 0.05) in As, Ba, Cu, Fe, Mn, Ni, Se and Zn in water, in all of the studied potentially toxic elements in sediment, and in As, Ba, Cd, Cr, Cu, Mn, Ni, Se, and Zn in the fish between the study and control areas. A chromosome assessment demonstrated 6 types of chromosome abnormalities, among which centric gap had the highest total number of chromosome abnormalities. Percentage of chromosome abnormalities, percentage of cells with chromosome abnormalities and serum liver enzymes in H. macrolepidota were significantly different ( p < 0.05) between the two studied areas and were higher in the contaminated fish than in the control fish. The observation of liver histopathological changes revealed cellular degeneration, such as nuclear damage, abnormal cytoplasmic mitochondria and the disintegration of rough endoplasmic reticulum. The results indicate that the contamination of potentially toxic elements in the Nam Kok River near the Sepon gold-copper mine area negatively affected chromosomes, serum liver enzymes and liver cell structures in H. macrolepidota .

Keywords: chromosome; environment; fish; lesion; metal; toxicity (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/11/5854/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/11/5854/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:11:p:5854-:d:565247

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().