The Rare, Unexpected Condition of a Twisted Leiomyoma in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: Etiopathogenesis, Diagnosis and Management. Our Experience and Narrative Review of the Literature

Federico Romano, Stefania Carlucci, Guglielmo Stabile, Giuseppe Mirenda, Mariateresa Mirandola, Francesco Paolo Mangino, Andrea Romano and Giuseppe Ricci
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Federico Romano: Institute for Maternal and Child Health, I.R.C.C.S. “Burlo Garofolo”, 34100 Trieste, Italy
Stefania Carlucci: Department of Obstetrics and Gynecology, Azienda Sanitaria Universitaria Giuliano-Isontina, San Polo Hospital, Gorizia-Monfalcone, 34127 Trieste, Italy
Guglielmo Stabile: Institute for Maternal and Child Health, I.R.C.C.S. “Burlo Garofolo”, 34100 Trieste, Italy
Giuseppe Mirenda: Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34137 Trieste, Italy
Mariateresa Mirandola: Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34137 Trieste, Italy
Francesco Paolo Mangino: Institute for Maternal and Child Health, I.R.C.C.S. “Burlo Garofolo”, 34100 Trieste, Italy
Andrea Romano: UCO Pathological Anatomy and Histology, Azienda Ospedaliera-Universitaria Ospedali Riuniti, 34129 Trieste, Italy
Giuseppe Ricci: Institute for Maternal and Child Health, I.R.C.C.S. “Burlo Garofolo”, 34100 Trieste, Italy

IJERPH, 2021, vol. 18, issue 11, 1-13

Abstract: Uterine leiomyomas are a common finding in medical practice, but their frequency changes drastically when contextualized in a syndrome, as in the following case. A 50-year-old woman with a known Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome presented at our clinic with abdominal pain located in the lower quadrants and scarcely responsive to analgesic therapy. A twisted gynecological pelvic mass was diagnosed, and management for prompt resolution was adopted. Histologically the mass was described as a leiomyoma. The aim of the present study is to share our experience and to review the literature to compare different manifestation of the disease and different approach used in the various centers. The additional novelty of the paper is the immunohistochemical study we carried out on the leiomyoma that is contrasted with the current etiopathogenetic theories.

Keywords: Mayer-Rokitansky-Küster-Hauser; leiomyoma; pelvic mass; torsion (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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