Reduced Self-Perception of Fatigue after Intake of Panax ginseng Root Extract (G115 ® ) Formulated with Vitamins and Minerals—An Open-Label Study

Anne-Laure Tardy, Beatrice Bois De Fer, Salvador Cañigueral, David Kennedy, Andrew Scholey, Simon Hitier, Alexia Aran and Etienne Pouteau
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Anne-Laure Tardy: Sanofi Global Consumer Health Care, 94250 Gentilly, France
Beatrice Bois De Fer: Sanofi Global Consumer Health Care, 94250 Gentilly, France
Salvador Cañigueral: Unit of Pharmacology, Pharmacognosy and Therapeutics, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08007 Barcelona, Spain
David Kennedy: Brain, Performance and Nutrition Research Centre, Faculty of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK
Andrew Scholey: Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC 3122, Australia
Simon Hitier: Sanofi Global Consumer Health Care, 94250 Gentilly, France
Alexia Aran: Sanofi Global Consumer Health Care, 94250 Gentilly, France
Etienne Pouteau: Sanofi Global Consumer Health Care, 94250 Gentilly, France

IJERPH, 2021, vol. 18, issue 12, 1-10

Abstract: Background: Unexplained fatigue is a common complaint. When underlying disease causes have been eliminated, lifestyle measures and supplementation can be indicated. Elaborating on clinical findings that G115 ® , a dry extract from the root of Panax ginseng, combined with vitamins and minerals could alleviate fatigue, this open label study aimed at assessing its effect on perceived fatigue and energy. Methods: Healthy adults self-reporting fatigue ( n = 103) completed the Multidimensional Fatigue Inventory questionnaire. They rated their perceptions of mental and physical fatigue, energy, performance, and stress at baseline and 15, 30, 60 and 90 days after a daily intake of 40 mg G115 ® formulated with vitamins and minerals. Results: Compared with baseline values, mean self-perception of general fatigue was reduced by ?7.55 units [95% CI: ?8.44; ?6.66] (?41.8%, p < 0.0001) at 90 days. All assessed perception ratings (mental and physical fatigue, reduced activity and motivation, performance, and stress) were significantly and steadily improved from two weeks after supplementation up to study’s end. Overall satisfaction with the ability of the product to reduce fatigue reached 85% at Day 90. Conclusion: Daily intake with G115 ® extract formulated with vitamins and minerals suggests an improvement of self-perception of fatigue and energy in a fatigued adult population.

Keywords: Panax ginseng G115 ® , fatigue; energy; vitamins; minerals (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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