Potential Improvement in Rehabilitation Quality of 2019 Novel Coronavirus by Isometric Training System; Is There “Muscle-Lung Cross-Talk”?

Hadi Nobari, Mohamad Fashi, Arezoo Eskandari, Jorge Pérez-Gómez and Katsuhiko Suzuki
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Hadi Nobari: Department of Physical Education and Sports, University of Granada, 18010 Granada, Spain
Mohamad Fashi: Department of Biological Sciences in Sports, Faculty of Sports Science and Health, Shahid Beheshti University, Tehran 198396-3113, Iran
Arezoo Eskandari: Department of Exercise Physiology, Faculty of Physical Education and Sports Science, Tehran University, Tehran 141793-5840, Iran
Jorge Pérez-Gómez: HEME Research Group, Faculty of Sport Sciences, University of Extremadura, 10003 Cáceres, Spain
Katsuhiko Suzuki: Faculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan

IJERPH, 2021, vol. 18, issue 12, 1-6

Abstract: The novel Coronavirus Disease 2019 (COVID-19) crisis is now present in more than 200 countries. It started in December 2019 and has, so far, led to more than 149, 470,968 cases, 3,152,121 deaths, and 127,133,013 survivors recovered by 28 April 2021. COVID-19 has a high morbidity, and mortality of 2%, on average, whereas most people are treated after a period of time. Some people who recover from COVID-19 are left with 20 to 30% decreased lung function. In this context, exercise focused on skeletal muscle with minimal lung involvement could potentially play an important role. Regular exercise protects against diseases associated with chronic low-grade systemic inflammation. This long-term effect of exercise may be ascribed to the anti-inflammatory response elicited by an acute bout of exercise, which is partly mediated by muscle-derived myokines. The isometric training system seems to have this feature, because this system is involved with the skeletal muscle as the target tissue. However, no studies have examined the effect of exercise on the treatment and recovery of COVID-19, and, more importantly, “muscle–lung cross-talk” as a mechanism for COVID-19 treatment. It is suggested that this theoretical construct be examined by researchers.

Keywords: COVID-19; immune response; chronic diseases; exercise; oxidative stress; anti-inflammatory treatment; fibroblast growth factor 21; cytokines; myokines (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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