Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors

Marianna Mile, László Balogh, Gábor Papp, József Márton Pucsok, Krisztina Szabó, Lilla Barna, Zoltán Csiki and István Lekli
Additional contact information
Marianna Mile: Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
László Balogh: Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Gábor Papp: Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
József Márton Pucsok: Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Krisztina Szabó: Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary
Lilla Barna: Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Zoltán Csiki: Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary
István Lekli: Institute of Healthcare Industry, University of Debrecen, 4032 Debrecen, Hungary

IJERPH, 2021, vol. 18, issue 12, 1-11

Abstract: Sarcopenia, defined as loss of muscle mass and strength, develops gradually with aging or after chronic disease. Efforts are ongoing to identify the best interventions that can slow down or stop sarcopenia. Nutrition-based interventions and exercise therapy may be beneficial; however, pharmacotherapy also could play a role. The effect of ACE inhibitors on physical performance is controversial. The present study investigates the impact of functional training on sarcopenia in the presence or absence of ACEi in elderly females. A total of 35 women over 65 years of age were selected for two groups on the basis that they were taking ACEi ( n = 18) or not ( n = 17). All subjects conducted a training program two times a week for 6 months. We examined various factors related to sarcopenia. After completing the short physical performance battery (SPPB) test, we found a significant improvement after 6 months of functional training. SPPB values of the ACEi group were significantly lower at the beginning of the study; however, we observed no difference between the SPPB results of the two groups after the training period. We conducted further studies to measure posture and spine mobility. Our Schober and Cobra test results revealed significantly improved spine mobility (both flexor and extensor) in both groups after 6 months of training. Furthermore, the grip strength of the hands, studied by an electric dynamometer, was significantly improved in both groups at the end of the training period. Our results indicated that functional training may improve body composition and muscle strength in patients diagnosed with sarcopenia. Furthermore, ACEi may be a helpful additional therapy in older adult patients suffering from severe sarcopenia.

Keywords: sarcopenia; elderly; ACE inhibitors; functional training (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/12/6594/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/12/6594/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:12:p:6594-:d:577843

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().