PM 2.5 and Diabetes in the Japanese Population

Mihye Lee and Sachiko Ohde
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Mihye Lee: Center for Clinical Academia, Graduate School of Public Health, Luke’s International University, 5th Floor 3-6-2, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
Sachiko Ohde: Center for Clinical Academia, Graduate School of Public Health, Luke’s International University, 5th Floor 3-6-2, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

IJERPH, 2021, vol. 18, issue 12, 1-9

Abstract: Growing evidence suggests that PM 2.5 is associated with diabetes mellitus (DM). Although DM is a major public health concern, there has not yet been a study of this association in Japan. We used health examination data from 66,885 individuals in Tokyo, Japan 2005–2019. Cox proportional hazards models were used to evaluate an association between annual exposure to PM 2.5 and glycated hemoglobin A 1c (HbA 1c ), or fasting plasma glucose (FPG). An increase of 1 ?g/m 3 in the annual average of PM 2.5 concentration was associated (HR = 1.029; 95% CI = 1.004–1.055) with an increase in diabetes (incident + prevalent). For incident DM, a greater PM 2.5 level was associated with more DM (HR = 1.029; 95% CI, 1.003–1.055). Compared to HbA 1c , FPG showed a stronger association with the annual exposure to PM 2.5 (HR = 1.065; 95% CI, 1.040–1.091). We found that greater exposure to PM 2.5 in the long-term was associated with an increased risk of diabetes, and that the magnitude of association became stronger as the exposure duration increased. Omorogieva Ojo

Keywords: diabetes mellitus; particulate matter; PM 2.5; air pollution; Japan; Tokyo (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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