The Impact of Nordic Walking on Bone Properties in Postmenopausal Women with Pre-Diabetes and Non-Alcohol Fatty Liver Disease

Xiaming Du, Chao Zhang, Xiangqi Zhang, Zhen Qi, Sulin Cheng and Shenglong Le
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Xiaming Du: Department of Orthopaedics, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, Shanghai 200433, China
Chao Zhang: Xidu Community Health Service Center of Fengxian District, Shanghai 201400, China
Xiangqi Zhang: Exercise Translational Medicine Center, Shanghai Jiao Tong University, Shanghai 200240, China
Zhen Qi: Exercise Translational Medicine Center, Shanghai Jiao Tong University, Shanghai 200240, China
Sulin Cheng: Exercise Translational Medicine Center, Shanghai Jiao Tong University, Shanghai 200240, China
Shenglong Le: Exercise Translational Medicine Center, Shanghai Jiao Tong University, Shanghai 200240, China

IJERPH, 2021, vol. 18, issue 14, 1-10

Abstract: This study investigated the impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease (NAFLD). A total of 63 eligible women randomly participated in the Nordic walking training (AEx, n = 33), or maintained their daily lifestyle (Con, n = 30) during intervention. Bone mineral content (BMC) and density (BMD) of whole body (WB), total femur (TF), femoral neck (FN), and lumbar spine (L2-4) were assessed by dual-energy X-ray absorptiometry. Serum osteocalcin, pentosidine, receptor activator of nuclear factor kappa-B ligand (RANKL) levels were analyzed by ELISA assay. After an 8.6-month intervention, the AEx group maintained their BMC TF , BMD TF , BMC L2?4 , and BMD L2?4 , and increased their BMC FN ( p = 0.016), while the Con group decreased their BMC TF ( p = 0.008), BMD TF ( p = 0.001), and BMD L2?4 ( p = 0.002). However, no significant group × time interaction was observed, except for BMD L2?4 ( p = 0.013). Decreased pentosidine was correlated with increased BMC WB ( r = ?0.352, p = 0.019). The intervention has no significant effect on osteocalcin and RANKL. Changing of bone mass was associated with changing of pentosidine, but not with osteocalcin and RANKL. Our results suggest that Nordic walking is effective in preventing bone loss among postmenopausal women with pre-diabetes and NAFLD.

Keywords: Nordic walking; postmenopausal women; fatty liver disease; bone markers; bone mineral density (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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