Colorectal Cancer in Young and Older Adults in Uruguay: Changes in Recent Incidence and Mortality Trends

Carina Musetti, Mariela Garau, Rafael Alonso, Marion Piñeros, Isabelle Soerjomataram and Enrique Barrios
Additional contact information
Carina Musetti: Registro Nacional de Cáncer Uruguay, Montevideo CP 11200, Uruguay
Mariela Garau: Registro Nacional de Cáncer Uruguay, Montevideo CP 11200, Uruguay
Rafael Alonso: Registro Nacional de Cáncer Uruguay, Montevideo CP 11200, Uruguay
Marion Piñeros: Cancer Surveillance Branch, International Agency for Research on Cancer, CP 69372 Lyon, France
Isabelle Soerjomataram: Cancer Surveillance Branch, International Agency for Research on Cancer, CP 69372 Lyon, France
Enrique Barrios: Registro Nacional de Cáncer Uruguay, Montevideo CP 11200, Uruguay

IJERPH, 2021, vol. 18, issue 15, 1-9

Abstract: Uruguay has the highest colorectal cancer incidence rates in Latin America. Previous studies reported a stable incidence and a slight increase in mortality among males. We aimed to assess colorectal cancer incidence (2002–2017) and mortality trends (1990–2017) by age groups and sex, using data from the National Cancer Registry. Annual percent changes (APCs) were estimated using joinpoint regression models. We included 27,561 colorectal cancer cases and 25,403 deaths. We found an increasing incidence among both males and females aged 40–49, with annual increases of 3.1% (95%CI: 1.21–5.03) and 2.1% (95%CI: 0.49–3.66), respectively, and an increasein the rate in older males (70+) of 0.60% (95%CI: 0.02–1.20) per year between 2002 and 2017. Mortality remained stable among those younger than 50, whereas it decreased for older females aged 50–69 and 70+ (APC: ?0.61% (?1.07–0.14) and ?0.68% (?1.02–0.34), respectively), and increased for the oldest males (70+; APC: 0.74 (0.47–1.01)). In conclusion, we found rising colorectal cancer incidence accompanied by stable mortality in young adults. Sex disparities were also found among the older adults, with a more favorable pattern for females. Exposures to dietary and lifestyle risk factors, and inequalities in access to and awareness of screening programs, are probably among the main underlying causes and deserve further investigation.

Keywords: colorectal cancer; incidence; mortality; trends; Uruguay; registry; national (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/15/8232/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/15/8232/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:15:p:8232-:d:607699

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().