Predictive Performance and Optimal Cut-Off Points of Blood Pressure for Identifying Arteriosclerosis among Adults in Eastern China

Lei Yu, Jiaxiang Yan, Chen Yang, Yanan Gao, Aiwen Wang and Huiming Huang
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Lei Yu: Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China
Jiaxiang Yan: Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China
Chen Yang: Department of Kinesiology and Physical Education, McGill University, Montreal, QC H2W 1S4, Canada
Yanan Gao: Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China
Aiwen Wang: Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China
Huiming Huang: Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China

IJERPH, 2021, vol. 18, issue 17, 1-10

Abstract: This study aimed to assess the predictive performance and establish optimal cut-off points of blood pressure for identifying arteriosclerosis in eastern Chinese adults. Brachial–ankle pulse wave velocity (baPWV) was utilized to evaluate arteriosclerosis. The predictive performance of blood pressure for arteriosclerosis was determined by the area under the curve (AUC) of receiver operating characteristics; the optimal blood pressure cut-off points were determined by Youden’s index. A logistic regression model was used to acquire the odds ratio (OR) of blood pressure for arteriosclerosis. The AUCs of blood pressure for identifying arteriosclerosis were 0.868 (95%CI: 0.860–0.875) for systolic blood pressure (SBP) and 0.835 (95%CI: 0.827–0.843) for diastolic blood pressure (DBP), both p < 0.01. The AUCs of women were higher than that of men (0.903 vs. 0.819 for SBP; 0.847 vs. 0.806 for DBP; Z test p < 0.05). The AUCs in the 18–39.9-years group were higher than that in the 40–59.9-years and 60–84-years groups (0.894 vs. 0.842 and 0.818 for SBP; 0.889 vs. 0.818 and 0.759 for DBP; Z test p < 0.05). The total optimal cut-off points of blood pressure for predicting arteriosclerosis were 123.5/73.5 mmHg (SBP/DBP) overall; 123.5/73.5 and 126.5/79.5 mmHg for women and men, respectively; and 120.5/73.5, 123.5/76.5, and 126.5/75.5 mmHg for 18–39.9-years, 40–59.9-years, and 60–84-years groups, respectively. Blood pressure indexes had a high predictive performance for identifying arteriosclerosis with the optimal cut-off point of 123.5/73.5 mmHg (SBP/DBP) in eastern Chinese adults. Women or the younger population have a higher predictive performance and lower cut-off points to identify arteriosclerosis.

Keywords: blood pressure; brachial-ankle pulse wave velocity; optimal cut-off point; arteriosclerosis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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