Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study

Gilbert Büsching, Zhongxing Zhang, Jean-Paul Schmid, Thomas Sigrist and Ramin Khatami
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Gilbert Büsching: Barmelweid Academy, Klinik Barmelweid AG, 5017 Barmelweid, Switzerland
Zhongxing Zhang: Barmelweid Academy, Klinik Barmelweid AG, 5017 Barmelweid, Switzerland
Jean-Paul Schmid: Department of Cardiology, Klinik Barmelweid AG, 5017 Barmelweid, Switzerland
Thomas Sigrist: Department of Pulmonology, Klinik Barmelweid AG, 5017 Barmelweid, Switzerland
Ramin Khatami: Barmelweid Academy, Klinik Barmelweid AG, 5017 Barmelweid, Switzerland

IJERPH, 2021, vol. 18, issue 17, 1-10

Abstract: Background: Severe and critically ill COVID-19 patients frequently need pulmonary rehabilitation (PR) after hospitalization. However, little is known about the effectiveness of PR in COVID-19 patients. Methods: We compared the performances in the six-min walk test (6MWT), chronic respiratory questionnaire (CRQ), and Functional Independence Measure (FIM) from inpatient PR between 51 COVID-19 patients and 51 other patients with common pneumonia. We used multivariate linear regression controlled for baseline values at entrance, age, sex, and cumulative illness rating scale. The odds ratios (ORs) of non-improvement/improvement in 6MWT (>30-m) and CRQ (>10-point) at discharge were compared between the two groups (Fisher’s exact test). Results: The two groups had similar improvements in 6MWT and CRQ, but the COVID-19 group achieved a 4-point higher FIM ( p -value = 0.004). The OR of non-improvement/improvement in 6MWT was 0.30 ( p -value = 0.13) between COVID-19 and controls; however, the odds of non-improvement in CRQ tended to be 3.02 times higher ( p -value = 0.075) in COVID-19 patients. Severe and critical COVID-19 patients had similar rehabilitation outcomes. Conclusions: Inpatient PR can effectively improve physical functions and life quality in COVID-19 patients, irrespective of disease severity. Whether the relatively low gains in CRQ is an indicator of chronic disease development in COVID-19 patients needs further studies.

Keywords: COVID-19; pulmonary rehabilitation; pneumonia; 6-MWT; CRQ; FIM (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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